ENSG00000160917


Homo sapiens

Features
Gene ID: ENSG00000160917
  
Biological name :CPSF4
  
Synonyms : cleavage and polyadenylation specific factor 4 / CPSF4 / O95639
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q22.1
Gene start: 99438922
Gene end: 99457371
  
Corresponding Affymetrix probe sets: 206688_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000401150
Ensembl peptide - ENSP00000396060
Ensembl peptide - ENSP00000401496
Ensembl peptide - ENSP00000415188
Ensembl peptide - ENSP00000402224
Ensembl peptide - ENSP00000292476
Ensembl peptide - ENSP00000392584
Ensembl peptide - ENSP00000395311
NCBI entrez gene - 10898     See in Manteia.
OMIM - 603052
RefSeq - XM_017011703
RefSeq - NM_001081559
RefSeq - NM_001318160
RefSeq - NM_001318161
RefSeq - NM_001318162
RefSeq - NM_006693
RefSeq - XM_011515755
RefSeq - XM_011515756
RefSeq - XM_011515757
RefSeq - XM_017011700
RefSeq - XM_017011701
RefSeq - XM_017011702
RefSeq Peptide - NP_001075028
RefSeq Peptide - NP_001305090
RefSeq Peptide - NP_001305091
RefSeq Peptide - NP_006684
RefSeq Peptide - NP_001305089
swissprot - H7C419
swissprot - B7Z7B0
swissprot - O95639
swissprot - C9K0K2
swissprot - C9JEV9
swissprot - F8WEL7
swissprot - H7C016
Ensembl - ENSG00000160917
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cpsf4ENSDARG00000020217Danio rerio
 CPSF4ENSGALG00000004714Gallus gallus
 Cpsf4ENSMUSG00000029625Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A6NMK7 / CPSF4L / cleavage and polyadenylation specific factor 4 likeENSG0000018795942
ZC3H3 / Q8IXZ2 / zinc finger CCCH-type containing 3ENSG0000001416425


Protein motifs (from Interpro)
Interpro ID Name
 IPR000571  Zinc finger, CCCH-type
 IPR001878  Zinc finger, CCHC-type
 IPR036855  Zinc finger, CCCH-type superfamily
 IPR036875  Zinc finger, CCHC-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006378 mRNA polyadenylation IBA
 biological_processGO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0031124 mRNA 3"-end processing TAS
 biological_processGO:0046778 modification by virus of host mRNA processing TAS
 biological_processGO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic IEA
 biological_processGO:0098789 pre-mRNA cleavage required for polyadenylation IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005847 mRNA cleavage and polyadenylation specificity factor complex IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0004521 endoribonuclease activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA Derived from an Intronless Transcript
Inhibition of Host mRNA Processing and RNA Silencing
tRNA processing in the nucleus
mRNA Splicing - Major Pathway
mRNA 3-end processing
Processing of Intronless Pre-mRNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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