ENSDARG00000021466


Danio rerio

Features
Gene ID: ENSDARG00000021466
  
Biological name :ireb2
  
Synonyms : ireb2 / iron-responsive element binding protein 2
  
Possible biological names infered from orthology : P48200 / Q811J3
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 6228496
Gene end: 6261693
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000117448
NCBI entrez gene - 652982     See in Manteia.
swissprot - F1QNR8
ZFIN ID - ZDB-GENE-051205-1
Ensembl - ENSDARG00000021466
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IREB2ENSGALG00000035462Gallus gallus
 IREB2ENSG00000136381Homo sapiens
 Ireb2ENSMUSG00000032293Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
aco1 / aconitase 1, soluble / P21399* / aconitase 1*ENSDARG0000002637654


Protein motifs (from Interpro)
Interpro ID Name
 IPR000573  Aconitase A/isopropylmalate dehydratase small subunit, swivel domain
 IPR001030  Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain
 IPR006249  Aconitase/Iron-responsive element-binding protein 2
 IPR015928  Aconitase/3-isopropylmalate dehydratase, swivel
 IPR015931  Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3
 IPR015932  Aconitase, domain 2
 IPR018136  Aconitase family, 4Fe-4S cluster binding site
 IPR029755  Iron regulatory protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006879 cellular iron ion homeostasis IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0017148 negative regulation of translation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0030350 iron-responsive element binding IEA
 molecular_functionGO:0030371 translation repressor activity IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Iron uptake and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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