ENSDARG00000026376


Danio rerio

Features
Gene ID: ENSDARG00000026376
  
Biological name :aco1
  
Synonyms : aco1 / aconitase 1, soluble
  
Possible biological names infered from orthology : aconitase 1 / P21399 / P28271
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 71463106
Gene end: 71486162
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000045252
NCBI entrez gene - 568448     See in Manteia.
RefSeq - NM_001034983
RefSeq Peptide - NP_001030155
swissprot - F1QM42
ZFIN ID - ZDB-GENE-031118-76
Ensembl - ENSDARG00000026376
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ACO1ENSGALG00000002162Gallus gallus
 ACO1ENSG00000122729Homo sapiens
 Aco1ENSMUSG00000028405Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ireb2 / iron-responsive element binding protein 2 / P48200* / Q811J3*ENSDARG0000002146659


Protein motifs (from Interpro)
Interpro ID Name
 IPR000573  Aconitase A/isopropylmalate dehydratase small subunit, swivel domain
 IPR001030  Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain
 IPR006249  Aconitase/Iron-responsive element-binding protein 2
 IPR015928  Aconitase/3-isopropylmalate dehydratase, swivel
 IPR015931  Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3
 IPR015932  Aconitase, domain 2
 IPR018136  Aconitase family, 4Fe-4S cluster binding site
 IPR029784  Iron regulatory protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006879 cellular iron ion homeostasis IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0010040 response to iron(II) ion IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003994 aconitate hydratase activity IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Iron uptake and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte hemoglobin complex decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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