ENSGALG00000002162


Gallus gallus

Features
Gene ID: ENSGALG00000002162
  
Biological name :ACO1
  
Synonyms : ACO1 / cytoplasmic aconitate hydratase
  
Possible biological names infered from orthology : aconitase 1 / P21399 / P28271
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 70963355
Gene end: 71000137
  
Corresponding Affymetrix probe sets: Gga.4139.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000055270
Ensembl peptide - ENSGALP00000003381
NCBI entrez gene - 373916     See in Manteia.
RefSeq - NM_001030536
RefSeq Peptide - NP_001025707
swissprot - F1NY25
swissprot - A0A1D5PQV0
Ensembl - ENSGALG00000002162
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aco1ENSDARG00000026376Danio rerio
 ACO1ENSG00000122729Homo sapiens
 Aco1ENSMUSG00000028405Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IREB2 / iron-responsive element-binding protein 2 / P48200* / Q811J3*ENSGALG0000003546260


Protein motifs (from Interpro)
Interpro ID Name
 IPR000573  Aconitase A/isopropylmalate dehydratase small subunit, swivel domain
 IPR001030  Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain
 IPR006249  Aconitase/Iron-responsive element-binding protein 2
 IPR015928  Aconitase/3-isopropylmalate dehydratase, swivel
 IPR015931  Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3
 IPR015932  Aconitase, domain 2
 IPR018136  Aconitase family, 4Fe-4S cluster binding site
 IPR029784  Iron regulatory protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006101 citrate metabolic process IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0006879 cellular iron ion homeostasis IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0010040 response to iron(II) ion IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0050892 intestinal absorption IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003994 aconitate hydratase activity IEA
 molecular_functionGO:0030350 iron-responsive element binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051538 3 iron, 4 sulfur cluster binding IEA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Iron uptake and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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