ENSDARG00000023151


Danio rerio

Features
Gene ID: ENSDARG00000023151
  
Biological name :ucp1
  
Synonyms : ucp1 / uncoupling protein 1
  
Possible biological names infered from orthology : P12242 / P25874 / uncoupling protein 1 (mitochondrial, proton carrier)
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 53374454
Gene end: 53388914
  
Corresponding Affymetrix probe sets: Dr.4905.1.S1_at (Zebrafish Array)   NM_199523_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000143642
Ensembl peptide - ENSDARP00000037614
NCBI entrez gene - 83908     See in Manteia.
RefSeq - NM_199523
RefSeq Peptide - NP_955817
swissprot - A0A286Y8Z7
swissprot - Q7ZVP4
ZFIN ID - ZDB-GENE-010503-1
Ensembl - ENSDARG00000023151
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 UCP1ENSG00000109424Homo sapiens
 Ucp1ENSMUSG00000031710Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ucp2 / uncoupling protein 2 / P55851* / P70406* / uncoupling protein 2 (mitochondrial, proton carrier)*ENSDARG0000004315471
ucp3 / uncoupling protein 3ENSDARG0000009120970
slc25a14 / solute carrier family 25 (mitochondrial carrier, brain), member 14 / Q9Z2B2* / O95258* / solute carrier family 25 member 14* / Mus musculus solute carrier family 25 (mitochondria...ENSDARG0000002668035
slc25a27 / solute carrier family 25, member 27 / O95847*ENSDARG0000004287334
si:ch1073-100f3.2 / Q9QZD8* / Q9UBX3* / SLC25A10* / AC139530.2* / solute carrier family 25 member 10* / solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10*ENSDARG0000009789030
slc25a11 / solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 / Q02978* / Q9CR62* / solute carrier family 25 member 11*ENSDARG0000003574129
slc25a10 / solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 / Q9UBX3* / AC139530.2* / solute carrier family 25 member 10*ENSDARG0000002507429


Protein motifs (from Interpro)
Interpro ID Name
 IPR002030  Mitochondrial carrier UCP-like
 IPR018108  Mitochondrial substrate/solute carrier
 IPR023395  Mitochondrial carrier domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006839 mitochondrial transport IEA
 biological_processGO:0009409 response to cold IBA
 biological_processGO:0071391 cellular response to estrogen stimulus IDA
 biological_processGO:1902600 proton transmembrane transport IEA
 biological_processGO:1990542 mitochondrial transmembrane transport IBA
 biological_processGO:1990845 adaptive thermogenesis IBA
 cellular_componentGO:0005743 mitochondrial inner membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 molecular_functionGO:0017077 oxidative phosphorylation uncoupler activity IBA


Pathways (from Reactome)
Pathway description
The fatty acid cycling model
The proton buffering model


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000023151 ucp1 / uncoupling protein 1 / P12242* / P25874* / uncoupling protein 1 (mitochondrial, proton carrier)*  / complex
 ENSDARG00000026680 slc25a14 / solute carrier family 25 (mitochondrial carrier, brain), member 14 / Q9Z2B2* / O95258* / solute carrier family 25 member 14* / Mus musculus solute carrier family 25 (mitochondria...  / complex
 ENSDARG00000043154 ucp2 / uncoupling protein 2 / P55851* / P70406* / uncoupling protein 2 (mitochondrial, proton carrier)*  / complex






 

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