ENSDARG00000024560


Danio rerio

Features
Gene ID: ENSDARG00000024560
  
Biological name :slc4a1b
  
Synonyms : slc4a1b / solute carrier family 4 (anion exchanger), member 1b (Diego blood group)
  
Possible biological names infered from orthology : P02730 / P04919 / SLC4A1 / solute carrier family 4 (anion exchanger), member 1 / solute carrier family 4 member 1 (Diego blood group)
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 10053852
Gene end: 10100504
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000072959
Ensembl peptide - ENSDARP00000124785
NCBI entrez gene - 561787     See in Manteia.
RefSeq - XM_005156076
RefSeq - NM_001168266
RefSeq Peptide - NP_001161738
swissprot - F8W2B8
swissprot - D1FTM8
ZFIN ID - ZDB-GENE-110215-2
Ensembl - ENSDARG00000024560
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P02730ENSG00000004939Homo sapiens
 P04919ENSMUSG00000006574Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
slc4a1a / solute carrier family 4 (anion exchanger), member 1a (Diego blood group) / P04919* / SLC4A1* / P02730* / solute carrier family 4 (anion exchanger), member 1* / solute carrier fami...ENSDARG0000001288164
slc4a2b / solute carrier family 4 (anion exchanger), member 2b / SLC4A2* / P04920* / solute carrier family 4 member 2* / solute carrier family 4 (anion exchanger), member 2*ENSDARG0000005233052
slc4a2a / solute carrier family 4 (anion exchanger), member 2a / SLC4A2* / P04920* / solute carrier family 4 member 2* / solute carrier family 4 (anion exchanger), member 2*ENSDARG0000002817351
slc4a3 / solute carrier family 4 (anion exchanger), member 3 / P48751* / solute carrier family 4 member 3*ENSDARG0000010400546
slc4a4a / solute carrier family 4 (sodium bicarbonate cotransporter), member 4a / Q9Y6R1* / SLC4A4* / O88343* / solute carrier family 4 member 4* / solute carrier family 4 (anion exchanger)...ENSDARG0000001373035
slc4a7 / solute carrier family 4, sodium bicarbonate cotransporter, member 7 / Q9Y6M7* / solute carrier family 4 member 7*ENSDARG0000007395234
slc4a4b / solute carrier family 4 (sodium bicarbonate cotransporter), member 4b / Q9Y6R1* / SLC4A4* / O88343* / solute carrier family 4 member 4* / solute carrier family 4 (anion exchanger)...ENSDARG0000004480834
slc4a8 / solute carrier family 4, sodium bicarbonate cotransporter, member 8 / Q8JZR6* / Q2Y0W8* / solute carrier family 4 member 8* / solute carrier family 4 (anion exchanger), member 8*ENSDARG0000001553133
slc4a5 / si:ch211-48m9.1 / solute carrier family 4 (sodium bicarbonate cotransporter), member 5 / Q9BY07* / solute carrier family 4 member 5*ENSDARG0000010438733
si:ch211-48m9.1 / Q9BY07* / SLC4A5* / solute carrier family 4 member 5*ENSDARG0000000277133
slc4a10a / solute carrier family 4, sodium bicarbonate transporter, member 10a / Q6U841* / Q5DTL9* / SLC4A10* / solute carrier family 4 member 10* / solute carrier family 4, sodium bicarbon...ENSDARG0000006313333
slc4a10b / solute carrier family 4, sodium bicarbonate transporter, member 10b / Q6U841* / Q5DTL9* / SLC4A10* / solute carrier family 4 member 10* / solute carrier family 4, sodium bicarbon...ENSDARG0000006030332
slc4a11 / solute carrier family 4, sodium borate transporter, member 11 / Q8NBS3* / A2AJN7* / solute carrier family 4 member 11* / Sodium bicarbonate transporter-like protein 11 *ENSDARG0000007553221


Protein motifs (from Interpro)
Interpro ID Name
 IPR001717  Anion exchange protein
 IPR002977  Anion exchange protein 1
 IPR003020  Bicarbonate transporter, eukaryotic
 IPR011531  Bicarbonate transporter, C-terminal
 IPR013769  Band 3 cytoplasmic domain
 IPR016152  Phosphotransferase/anion transporter
 IPR018241  Anion exchange, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006820 anion transport IEA
 biological_processGO:0015698 inorganic anion transport IEA
 biological_processGO:0015701 bicarbonate transport IEA
 biological_processGO:0042891 antibiotic transport IEA
 biological_processGO:0051453 regulation of intracellular pH IBA
 biological_processGO:0070509 calcium ion import IMP
 biological_processGO:0098656 anion transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005452 inorganic anion exchanger activity IEA
 molecular_functionGO:0008509 anion transmembrane transporter activity IEA
 molecular_functionGO:0008510 sodium:bicarbonate symporter activity IBA
 molecular_functionGO:0015106 bicarbonate transmembrane transporter activity IMP
 molecular_functionGO:0015301 anion:anion antiporter activity IMP
 molecular_functionGO:0042895 antibiotic transmembrane transporter activity IMP


Pathways (from Reactome)
Pathway description
Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Bicarbonate transporters


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009367 neuromast hair cell neuromast hair cell calcium ion import decreased efficacy , abnormal
neuromast hair cell decreased amount , abnormal
neuromast hair cell increased amount , abnormal
neuromast hair cell nucleus morphology , abnormal
neuromast hair cell stereocilium unfused from neuromast hair cell stereocilium, abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000012881 slc4a1a / solute carrier family 4 (anion exchanger), member 1a (Diego blood group) / P04919* / SLC4A1* / P02730* / solute carrier family 4 (anion exchanger), member 1* / solute carrier fami...  / complex
 ENSDARG00000024560 slc4a1b / solute carrier family 4 (anion exchanger), member 1b (Diego blood group) / P04919* / SLC4A1* / P02730* / solute carrier family 4 (anion exchanger), member 1* / solute carrier fami...  / complex






 

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