ENSDARG00000025436


Danio rerio

Features
Gene ID: ENSDARG00000025436
  
Biological name :msrb1a
  
Synonyms : methionine sulfoxide reductase B1a / msrb1a / Q802G6
  
Possible biological names infered from orthology : methionine sulfoxide reductase B1 / MSRB1 / Mus musculus methionine sulfoxide reductase B1 (Msrb1), transcript variant 2, mRNA. / Q9JLC3 / Q9NZV6
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 18798431
Gene end: 18805294
  
Corresponding Affymetrix probe sets: Dr.147.1.A1_at (Zebrafish Array)   Dr.16417.1.A1_at (Zebrafish Array)   Dr.24956.1.S1_at (Zebrafish Array)   NM_178288_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000122736
Ensembl peptide - ENSDARP00000115071
Ensembl peptide - ENSDARP00000121192
NCBI entrez gene - 352916     See in Manteia.
RefSeq - NM_178288
RefSeq Peptide - NP_840073
swissprot - A0A1I8S0K7
swissprot - Q6P6Y5
swissprot - Q802G6
ZFIN ID - ZDB-GENE-030411-3
Ensembl - ENSDARG00000025436
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MSRB1ENSGALG00000005414Gallus gallus
 MSRB1ENSG00000198736Homo sapiens
 Msrb1ENSMUSG00000075705Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
msrb1b / methionine sulfoxide reductase B1b / MSRB1* / Q9JLC3* / Q9NZV6* / methionine sulfoxide reductase B1* / Mus musculus methionine sulfoxide reductase B1 (Msrb1), transcript variant 2, mRNA.*ENSDARG0000004516074


Protein motifs (from Interpro)
Interpro ID Name
 IPR002579  Peptide methionine sulphoxide reductase MrsB
 IPR011057  Mss4-like superfamily
 IPR028427  Peptide methionine sulfoxide reductase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0030041 actin filament polymerization ISS
 biological_processGO:0030091 protein repair IEA
 biological_processGO:0045087 innate immune response ISS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0015629 actin cytoskeleton ISS
 molecular_functionGO:0003779 actin binding ISS
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor IEA
 molecular_functionGO:0033743 peptide-methionine (R)-S-oxide reductase activity IEA
 molecular_functionGO:0033745 L-methionine-(R)-S-oxide reductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Protein repair


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000044125 txn / thioredoxin / Txn1* / Q6A555* / Q86VQ3* / TXNDC8* / P10599* / P10639* / Q69AB2* / TXNDC2* / thioredoxin 1* / thioredoxin domain containing 2* / thioredoxin domain containing 8* / thio...  / reaction
 ENSDARG00000031435 zgc:56493 / TXN* / Txn1* / Q6A555* / Q86VQ3* / P10639* / Q69AB2* / TXNDC2* / TXNDC8* / P10599* / thioredoxin* / thioredoxin 1* / thioredoxin domain containing 2* / thioredoxin domain contai...  / reaction






 

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