ENSG00000198736


Homo sapiens

Features
Gene ID: ENSG00000198736
  
Biological name :MSRB1
  
Synonyms : methionine sulfoxide reductase B1 / MSRB1 / Q9NZV6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p13.3
Gene start: 1938210
Gene end: 1943326
  
Corresponding Affymetrix probe sets: 217977_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000382657
Ensembl peptide - ENSP00000480943
Ensembl peptide - ENSP00000457320
Ensembl peptide - ENSP00000456557
Ensembl peptide - ENSP00000355084
NCBI entrez gene - 51734     See in Manteia.
OMIM - 606216
RefSeq - NM_016332
RefSeq Peptide - NP_057416
swissprot - H3BTT6
swissprot - A8MYR2
swissprot - Q9NZV6
swissprot - A0A087WXE3
swissprot - H3BS64
Ensembl - ENSG00000198736
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 msrb1aENSDARG00000025436Danio rerio
 msrb1bENSDARG00000045160Danio rerio
 MSRB1ENSGALG00000005414Gallus gallus
 Msrb1ENSMUSG00000075705Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002579  Peptide methionine sulphoxide reductase MrsB
 IPR011057  Mss4-like superfamily
 IPR028427  Peptide methionine sulfoxide reductase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0030041 actin filament polymerization IEA
 biological_processGO:0030091 protein repair IEA
 biological_processGO:0045087 innate immune response ISS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor IEA
 molecular_functionGO:0033743 peptide-methionine (R)-S-oxide reductase activity IEA
 molecular_functionGO:0033745 L-methionine-(R)-S-oxide reductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070191 methionine-R-sulfoxide reductase activity IEA


Pathways (from Reactome)
Pathway description
Protein repair


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000136810 TXN / P10599 / thioredoxin  / reaction






 

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