ENSDARG00000028533


Danio rerio

Features
Gene ID: ENSDARG00000028533
  
Biological name :macf1a
  
Synonyms : macf1a / microtubule-actin crosslinking factor 1a
  
Possible biological names infered from orthology : MACF1 / microtubule-actin crosslinking factor 1 / Q9UPN3
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 35039902
Gene end: 35340027
  
Corresponding Affymetrix probe sets: Dr.1815.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000126497
Ensembl peptide - ENSDARP00000054273
Ensembl peptide - ENSDARP00000116989
Ensembl peptide - ENSDARP00000126390
swissprot - K7DYG8
swissprot - A0A0R4IDL6
swissprot - E9QFS3
swissprot - F1RA35
swissprot - K7DY63
ZFIN ID - ZDB-GENE-030131-3606
Ensembl - ENSDARG00000028533
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MACF1ENSGALG00000003693Gallus gallus
 MACF1ENSG00000127603Homo sapiens
 Macf1ENSMUSG00000028649Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DST / dystonin / Q03001*ENSDARG0000010185832
pleca / plectin a / PLEC* / Q9QXS1* / Q15149* / plectin*ENSDARG0000006259017
plecb / plectin b / PLEC* / Q9QXS1* / Q15149* / plectin*ENSDARG0000002198716
si:ch211-165e15.1 / DST* / Q03001* / Q91ZU6* / dystonin*ENSDARG000001024067
dspa / desmoplakin a / DSP* / E9Q557* / P15924* / desmoplakin*ENSDARG000000223097
evpla / envoplakin a / EVPL* / Q92817* / envoplakin*ENSDARG000000198086
CABZ01044281.1 / DST* / Q03001* / Q91ZU6* / dystonin*ENSDARG000001159566
wu:fi04e12 / DSP* / P15924* / desmoplakin*ENSDARG000000766736
ppl / periplakin / O60437*ENSDARG000001010435
eppk1 / epiplakin 1ENSDARG000000963595
CABZ01044277.1 / DST* / Q03001* / dystonin*ENSDARG000000986315


Protein motifs (from Interpro)
Interpro ID Name
 IPR001589  Actinin-type actin-binding domain, conserved site
 IPR001715  Calponin homology domain
 IPR002017  Spectrin repeat
 IPR002048  EF-hand domain
 IPR003108  GAR domain
 IPR011992  EF-hand domain pair
 IPR018159  Spectrin/alpha-actinin
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009798 axis specification IMP
 biological_processGO:0060832 oocyte animal/vegetal axis specification IMP
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008017 microtubule binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001175 blastodisc blastodisc absent , abnormal
Show

 ZFA:0001565 oocyte stage II oocyte stage II nucleus mislocalised , abnormal
oocyte stage II mitochondrion mislocalised , abnormal
oocyte stage II endoplasmic reticulum mislocalised , abnormal
oocyte stage II cytoplasmic part mislocalised , abnormal
oocyte stage II cortical granule mislocalised , abnormal
Show

 ZFA:0001566 oocyte stage III oocyte stage III cortical granule mislocalised , abnormal
Show

 ZFA:0001567 oocyte stage I oocyte stage I physical object quality , abnormal
oocyte stage I nucleus mislocalised , abnormal
oocyte stage I mitochondrion mislocalised , abnormal
oocyte stage I endoplasmic reticulum mislocalised , abnormal
oocyte stage I microtubule mislocalised , abnormal
oocyte stage I mitochondrial cloud increased size , abnormal
oocyte stage I mitochondrial cloud mislocalised , abnormal
Show

 ZFA:0001570 unfertilized egg unfertilized egg decreased size , abnormal
unfertilized egg malformed , abnormal
unfertilized egg cytoplasm mislocalised , abnormal
unfertilized egg chorion malformed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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