ENSDARG00000021987


Danio rerio

Features
Gene ID: ENSDARG00000021987
  
Biological name :plecb
  
Synonyms : plecb / plectin b
  
Possible biological names infered from orthology : PLEC / plectin / Q15149 / Q9QXS1
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 5251768
Gene end: 5497474
  
Corresponding Affymetrix probe sets: Dr.10612.1.A1_at (Zebrafish Array)   Dr.3124.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000112940
Ensembl peptide - ENSDARP00000155551
Ensembl peptide - ENSDARP00000134788
Ensembl peptide - ENSDARP00000003373
NCBI entrez gene - 100321011     See in Manteia.
RefSeq - XM_021466832
RefSeq - XM_021466841
RefSeq - XM_021466842
RefSeq - XM_021466843
RefSeq - XM_021466844
RefSeq - XM_009292043
RefSeq - XM_021466827
RefSeq - XM_021466828
RefSeq - XM_021466829
RefSeq - XM_021466830
RefSeq - XM_021466831
RefSeq - XM_021466833
RefSeq - XM_021466834
RefSeq - XM_021466835
RefSeq - XM_021466836
RefSeq - XM_021466837
RefSeq - XM_021466838
RefSeq - XM_021466839
RefSeq - XM_021466840
swissprot - E9QCV2
swissprot - E7F4T0
swissprot - A0A0R4IJ71
ZFIN ID - ZDB-GENE-100917-2
Ensembl - ENSDARG00000021987
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLECENSG00000178209Homo sapiens
 PlecENSMUSG00000022565Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pleca / plectin a / PLEC* / Q9QXS1* / Q15149* / plectin*ENSDARG0000006259073
macf1a / microtubule-actin crosslinking factor 1a / MACF1* / Q9UPN3* / microtubule-actin crosslinking factor 1*ENSDARG0000002853321
wu:fi04e12 / DSP* / P15924* / desmoplakin*ENSDARG0000007667315
dspa / desmoplakin a / DSP* / E9Q557* / P15924* / desmoplakin*ENSDARG0000002230915
eppk1 / epiplakin 1ENSDARG0000009635912
CABZ01044281.1 / DST* / Q03001* / Q91ZU6* / dystonin*ENSDARG0000011595610
evpla / envoplakin a / EVPL* / Q92817* / envoplakin*ENSDARG000000198089
ppl / periplakin / O60437*ENSDARG000001010438
si:ch211-165e15.1 / DST* / Q03001* / Q91ZU6* / dystonin*ENSDARG000001024067
CABZ01044277.1 / DST* / Q03001* / dystonin*ENSDARG000000986316
DST / dystonin / Q03001*ENSDARG000001018586


Protein motifs (from Interpro)
Interpro ID Name
 IPR001101  Plectin repeat
 IPR001589  Actinin-type actin-binding domain, conserved site
 IPR001715  Calponin homology domain
 IPR018159  Spectrin/alpha-actinin
 IPR030269  Plectin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007519 skeletal muscle tissue development IMP
 biological_processGO:0007626 locomotory behavior IMP
 biological_processGO:0030239 myofibril assembly IMP
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0003779 actin binding IEA


Pathways (from Reactome)
Pathway description
Assembly of collagen fibrils and other multimeric structures
Caspase-mediated cleavage of cytoskeletal proteins
Type I hemidesmosome assembly


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased mobility , abnormal
Show

 ZFA:0001115 trunk trunk curved , abnormal
Show

 ZFA:0005277 skeletal muscle skeletal muscle refractivity , abnormal
skeletal muscle nucleus circular , abnormal
skeletal muscle sarcomere disorganized , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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