ENSDARG00000062590


Danio rerio

Features
Gene ID: ENSDARG00000062590
  
Biological name :pleca
  
Synonyms : pleca / plectin a
  
Possible biological names infered from orthology : PLEC / plectin / Q15149 / Q9QXS1
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 22407819
Gene end: 22621991
  
Corresponding Affymetrix probe sets: Dr.11514.1.A1_at (Zebrafish Array)   Dr.13400.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000145064
Ensembl peptide - ENSDARP00000156261
Ensembl peptide - ENSDARP00000156014
Ensembl peptide - ENSDARP00000150293
Ensembl peptide - ENSDARP00000145708
Ensembl peptide - ENSDARP00000145363
Ensembl peptide - ENSDARP00000085102
Ensembl peptide - ENSDARP00000085112
Ensembl peptide - ENSDARP00000122816
Ensembl peptide - ENSDARP00000126033
Ensembl peptide - ENSDARP00000136093
Ensembl peptide - ENSDARP00000144502
NCBI entrez gene - 567639     See in Manteia.
RefSeq - NM_001100032
RefSeq - XM_021468101
RefSeq - XM_021468104
RefSeq - XM_021468105
RefSeq Peptide - NP_001093502
swissprot - I3ISY3
swissprot - E7F8G7
swissprot - A5WV03
swissprot - A5WV02
swissprot - A0A286YBE9
swissprot - A0A0R4INC4
ZFIN ID - ZDB-GENE-030131-8984
Ensembl - ENSDARG00000062590
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLECENSG00000178209Homo sapiens
 PlecENSMUSG00000022565Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
plecb / plectin b / PLEC* / Q9QXS1* / Q15149* / plectin*ENSDARG0000002198772
macf1a / microtubule-actin crosslinking factor 1a / MACF1* / Q9UPN3* / microtubule-actin crosslinking factor 1*ENSDARG0000002853321
dspa / desmoplakin a / DSP* / E9Q557* / P15924* / desmoplakin*ENSDARG0000002230915
wu:fi04e12 / DSP* / P15924* / desmoplakin*ENSDARG0000007667314
eppk1 / epiplakin 1ENSDARG0000009635911
CABZ01044281.1 / DST* / Q03001* / Q91ZU6* / dystonin*ENSDARG0000011595610
evpla / envoplakin a / EVPL* / Q92817* / envoplakin*ENSDARG000000198089
ppl / periplakin / O60437*ENSDARG000001010438
si:ch211-165e15.1 / DST* / Q03001* / Q91ZU6* / dystonin*ENSDARG000001024067
CABZ01044277.1 / DST* / Q03001* / dystonin*ENSDARG000000986316
DST / dystonin / Q03001*ENSDARG000001018586


Protein motifs (from Interpro)
Interpro ID Name
 IPR001101  Plectin repeat
 IPR001589  Actinin-type actin-binding domain, conserved site
 IPR001715  Calponin homology domain
 IPR018159  Spectrin/alpha-actinin
 IPR030269  Plectin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007519 skeletal muscle tissue development IMP
 biological_processGO:0007626 locomotory behavior IMP
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003779 actin binding IEA


Pathways (from Reactome)
Pathway description
Assembly of collagen fibrils and other multimeric structures
Caspase-mediated cleavage of cytoskeletal proteins
Type I hemidesmosome assembly


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0001094 whole organism whole organism decreased mobility , abnormal
Show

 ZFA:0001115 trunk trunk curved , abnormal
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 ZFA:0005277 skeletal muscle skeletal muscle refractivity , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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