ENSDARG00000031761


Danio rerio

Features
Gene ID: ENSDARG00000031761
  
Biological name :dab2
  
Synonyms : dab2 / Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
  
Possible biological names infered from orthology : DAB2, clathrin adaptor protein / P98082
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 32323775
Gene end: 32338872
  
Corresponding Affymetrix probe sets: Dr.9443.1.A1_at (Zebrafish Array)   NM_205757_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000078297
Ensembl peptide - ENSDARP00000113909
Ensembl peptide - ENSDARP00000028118
Ensembl peptide - ENSDARP00000047669
NCBI entrez gene - 404040     See in Manteia.
RefSeq - NM_001327871
RefSeq - NM_001327872
RefSeq - NM_205757
RefSeq Peptide - NP_991320
RefSeq Peptide - NP_001314800
RefSeq Peptide - NP_001314801
swissprot - B8A567
swissprot - B8A566
ZFIN ID - ZDB-GENE-040303-1
Ensembl - ENSDARG00000031761
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DAB2ENSGALG00000003803Gallus gallus
 DAB2ENSG00000153071Homo sapiens
 Dab2ENSMUSG00000022150Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:ch211-204c21.1 / DAB2* / P98082* / DAB2, clathrin adaptor protein*ENSDARG0000005309140
dab1a / Dab, reelin signal transducer, homolog 1a (Drosophila)ENSDARG0000005993930
dab1b / Dab, reelin signal transducer, homolog 1b (Drosophila)ENSDARG0000000329021


Protein motifs (from Interpro)
Interpro ID Name
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0001944 vasculature development IMP
 biological_processGO:0006898 receptor-mediated endocytosis IMP
 biological_processGO:0007219 Notch signaling pathway IGI
 biological_processGO:0030510 regulation of BMP signaling pathway IMP


Pathways (from Reactome)
Pathway description
Gap junction degradation
Formation of annular gap junctions
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle cardiac muscle cell decreased amount , abnormal
Show

 ZFA:0000029 hindbrain hindbrain increased amount , abnormal
Show

 ZFA:0000109 forebrain forebrain increased amount , abnormal
Show

 ZFA:0000114 heart heart physical object quality , abnormal
heart physical object quality , ameliorated
Show

 ZFA:0000128 midbrain midbrain increased amount , abnormal
Show

 ZFA:0000150 pronephric duct pronephric duct early endosome absent , abnormal
Show

 ZFA:0000151 pronephros pronephros anterior region increased amount , abnormal
Show

 ZFA:0000471 atrium atrium cardiac muscle cell decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism wholly ventralized , abnormal
whole organism morphology , ameliorated
whole organism malformed , abnormal
whole organism increased amount , abnormal
whole organism decreased amount , abnormal
Show

 ZFA:0001286 caudal vein plexus caudal vein plexus angiogenic sprout decreased amount , abnormal
caudal vein plexus morphology , abnormal
caudal vein plexus aplastic , abnormal
Show

 ZFA:0005037 post-vent vasculature post-vent vasculature vasculature development decreased process quality , abnormal
Show

 ZFA:0005249 vasculature vasculature posterior region increased amount , abnormal
Show

 ZFA:0009316 cardiac muscle cell cardiac muscle cell amount , ameliorated
cardiac muscle cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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