ENSGALG00000003803


Gallus gallus

Features
Gene ID: ENSGALG00000003803
  
Biological name :DAB2
  
Synonyms : DAB2 / DAB2, clathrin adaptor protein
  
Possible biological names infered from orthology : P98082
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 12349471
Gene end: 12359241
  
Corresponding Affymetrix probe sets: Gga.12381.1.S1_s_at (Chicken Array)   GgaAffx.25988.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000006023
NCBI entrez gene - 427449     See in Manteia.
RefSeq - XM_015277538
RefSeq - XM_015277539
RefSeq - XM_015277541
RefSeq - XM_015277542
RefSeq - XM_015277543
RefSeq - XM_015277537
swissprot - E1C8Z9
Ensembl - ENSGALG00000003803
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dab2ENSDARG00000031761Danio rerio
 si:ch211-204c21.1ENSDARG00000053091Danio rerio
 DAB2ENSG00000153071Homo sapiens
 Dab2ENSMUSG00000022150Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DAB1 / disabled homolog 1 / O75553* / P97318* / DAB1, reelin adaptor protein*ENSGALG0000001085726


Protein motifs (from Interpro)
Interpro ID Name
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition IEA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0032091 negative regulation of protein binding IEA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0035026 leading edge cell differentiation IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045807 positive regulation of endocytosis IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0060391 positive regulation of SMAD protein signal transduction IEA
 biological_processGO:0060766 negative regulation of androgen receptor signaling pathway IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:1903077 negative regulation of protein localization to plasma membrane IEA
 biological_processGO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway IEA
 biological_processGO:2000370 positive regulation of clathrin-dependent endocytosis IEA
 biological_processGO:2000643 positive regulation of early endosome to late endosome transport IEA
 cellular_componentGO:0001650 fibrillar center IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005905 clathrin-coated pit IEA
 cellular_componentGO:0030136 clathrin-coated vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0070022 transforming growth factor beta receptor complex IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0035615 clathrin adaptor activity IEA
 molecular_functionGO:0038024 cargo receptor activity IEA
 molecular_functionGO:0046332 SMAD binding IEA


Pathways (from Reactome)
Pathway description
Gap junction degradation
Formation of annular gap junctions
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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