ENSDARG00000032619


Danio rerio

Features
Gene ID: ENSDARG00000032619
  
Biological name :tob1a
  
Synonyms : tob1a / transducer of ERBB2, 1a
  
Possible biological names infered from orthology : P50616 / Protein Tob1 / Q61471 / TOB1 / transducer of ERBB2, 1
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 18185616
Gene end: 18189283
  
Corresponding Affymetrix probe sets: Dr.4590.1.A1_at (Zebrafish Array)   NM_198363_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000049239
NCBI entrez gene - 386629     See in Manteia.
RefSeq - NM_198363
RefSeq Peptide - NP_938177
swissprot - Q7SZR1
ZFIN ID - ZDB-GENE-031030-4
Ensembl - ENSDARG00000032619
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TOB1ENSGALG00000007364Gallus gallus
 TOB1ENSG00000141232Homo sapiens
 Tob1ENSMUSG00000037573Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tob1b / transducer of ERBB2, 1b / TOB1* / Q61471* / P50616* / Protein Tob1 * / transducer of ERBB2, 1*ENSDARG0000002137284
btg1 / B-cell translocation gene 1, anti-proliferative / P62324* / P62325* / Btg1-ps2* / Btg1-ps1* / Protein BTG1 * / BTG anti-proliferation factor 1* / B cell translocation gene 1, anti-pr...ENSDARG0000002724920
btg3 / B-cell translocation gene 3 / Q14201* / Gm7334* / P50615* / Protein BTG3 * / predicted gene 7334* / BTG anti-proliferation factor 3*ENSDARG0000006906519
si:dkey-42i9.4ENSDARG0000000804918
btg4 / B-cell translocation gene 4 / O70552* / Q9NY30* / Protein BTG4 * / BTG anti-proliferation factor 4*ENSDARG0000003517118
btg2 / B-cell translocation gene 2 / P78543* / BTG anti-proliferation factor 2*ENSDARG0000002029817
si:dkey-79d12.5ENSDARG0000004028416


Protein motifs (from Interpro)
Interpro ID Name
 IPR002087  Anti-proliferative protein
 IPR015676  Tob1/2
 IPR015677  Tob1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009953 dorsal/ventral pattern formation IMP
 biological_processGO:0016055 Wnt signaling pathway IGI
 biological_processGO:0030509 BMP signaling pathway IDA
 biological_processGO:0060070 canonical Wnt signaling pathway IGI
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0003714 transcription corepressor activity IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000077 tail bud tail bud umbonate , abnormal
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 ZFA:0001069 ventral fin fold ventral fin fold decreased size , abnormal
Show

 ZFA:0001094 whole organism whole organism wholly dorsalized , abnormal
Show

 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
post-vent region malformed , abnormal
post-vent region kinked , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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