ENSGALG00000007364


Gallus gallus

Features
Gene ID: ENSGALG00000007364
  
Biological name :TOB1
  
Synonyms : TOB1 / transducer of ERBB2, 1
  
Possible biological names infered from orthology : P50616 / Protein Tob1 / Q61471
  
Species: Gallus gallus
  
Chr. number: 18
Strand: 1
Band:
Gene start: 10170957
Gene end: 10172858
  
Corresponding Affymetrix probe sets: Gga.1160.1.S1_at (Chicken Array)   Gga.1160.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000059194
Ensembl peptide - ENSGALP00000011895
NCBI entrez gene - 395225     See in Manteia.
RefSeq - XM_015295379
RefSeq - NM_001001467
RefSeq Peptide - NP_001001467
swissprot - Q90VW0
swissprot - A0A1L1RKA7
Ensembl - ENSGALG00000007364
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tob1aENSDARG00000032619Danio rerio
 tob1bENSDARG00000021372Danio rerio
 TOB1ENSG00000141232Homo sapiens
 Tob1ENSMUSG00000037573Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TOB2 / transducer of ERBB2, 2 / Q14106* / Q9JM55*ENSGALG0000001195762
BTG1 / P34743 / Protein BTG1 / P62324* / P62325* / Btg1-ps2* / Btg1-ps1* / BTG anti-proliferation factor 1* / B cell translocation gene 1, anti-proliferative, pseudogene 1* / B cell transl...ENSGALG0000001127621
ENSGALG0000000467618
BTG4 / BTG anti-proliferation factor 4 / O70552* / Q9NY30* / Protein BTG4 *ENSGALG0000000761818
BTG2 / BTG anti-proliferation factor 2 / P78543* / Q04211* / Protein BTG2 *ENSGALG0000002685817


Protein motifs (from Interpro)
Interpro ID Name
 IPR002087  Anti-proliferative protein
 IPR015676  Tob1/2
 IPR015677  Tob1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0017148 negative regulation of translation IEA
 biological_processGO:0030509 BMP signaling pathway IBA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IEA
 biological_processGO:0045668 negative regulation of osteoblast differentiation IEA
 biological_processGO:0060212 negative regulation of nuclear-transcribed mRNA poly(A) tail shortening IEA
 biological_processGO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening IEA
 biological_processGO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IEA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030014 CCR4-NOT complex IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0030971 receptor tyrosine kinase binding IEA
 molecular_functionGO:0046332 SMAD binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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