ENSDARG00000034624


Danio rerio

Features
Gene ID: ENSDARG00000034624
  
Biological name :nuf2
  
Synonyms : nuf2 / NUF2, NDC80 kinetochore complex component, homolog / Q7ZW63
  
Possible biological names infered from orthology : Mus musculus NUF2, NDC80 kinetochore complex component (Nuf2), transcript variant 2, mRNA. / NUF2, NDC80 kinetochore complex component / Q99P69 / Q9BZD4
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 429776
Gene end: 438518
  
Corresponding Affymetrix probe sets: Dr.15726.1.S1_at (Zebrafish Array)   NM_200310_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000040811
Ensembl peptide - ENSDARP00000119923
Ensembl peptide - ENSDARP00000114276
NCBI entrez gene - 393280     See in Manteia.
RefSeq - NM_200310
RefSeq - XM_005155671
RefSeq Peptide - NP_956604
swissprot - E9QD03
swissprot - Q7ZW63
swissprot - E9QBK4
ZFIN ID - ZDB-GENE-040426-1121
Ensembl - ENSDARG00000034624
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NUF2ENSGALG00000003438Gallus gallus
 NUF2ENSG00000143228Homo sapiens
 Nuf2ENSMUSG00000026683Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005549  Kinetochore protein Nuf2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0031262 Ndc80 complex IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
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 ZFA:0001094 whole organism whole organism viability , abnormal
whole organism necrotic , abnormal
whole organism atrophied , abnormal
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 ZFA:0001114 head head flat , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000077822 si:dkey-6i22.5 / PMF1* / Q6P1K2* / Q9CPV5* / PMF1-BGLAP* / PMF1-BGLAP readthrough* / polyamine modulated factor 1*  / complex
 ENSDARG00000024471 nsl1 / NSL1, MIS12 kinetochore complex component / Q96IY1*  / complex
 ENSDARG00000089922 dsn1 / DSN1 homolog, MIS12 kinetochore complex component / Q9H410*  / complex
 ENSDARG00000071694 ndc80 / Q6DRJ7 / NDC80 kinetochore complex component / O14777* / Q9D0F1* / Kinetochore *  / complex
 ENSDARG00000093622 spc24 / Q503N2 / SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) / Q9D083* / Q8NBT2* / Kinetochore protein Spc24 * / SPC24, NDC80 kinetochore complex component*  / complex
 ENSDARG00000078433 spc25 / SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) / Q9HBM1* / Q3UA16* / Kinetochore protein Spc25 * / SPC25, NDC80 kinetochore complex component*  / complex






 

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