ENSDARG00000024471


Danio rerio

Features
Gene ID: ENSDARG00000024471
  
Biological name :nsl1
  
Synonyms : nsl1 / NSL1, MIS12 kinetochore complex component
  
Possible biological names infered from orthology : Q96IY1
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 37814345
Gene end: 37820939
  
Corresponding Affymetrix probe sets: Dr.17968.1.S1_at (Zebrafish Array)   NM_001025521_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000030404
NCBI entrez gene - 562522     See in Manteia.
RefSeq - NM_001025521
RefSeq Peptide - NP_001020692
swissprot - Q5RGS8
ZFIN ID - ZDB-GENE-041014-362
Ensembl - ENSDARG00000024471
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NSL1ENSGALG00000009814Gallus gallus
 NSL1ENSG00000117697Homo sapiens
 Nsl1ENSMUSG00000062510Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013950  Kinetochore Mis14/Nsl1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000070 mitotic sister chromatid segregation IEA
 cellular_componentGO:0000444 MIS12/MIND type complex IBA
 cellular_componentGO:0000776 kinetochore IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000071694 ndc80 / Q6DRJ7 / NDC80 kinetochore complex component / O14777* / Q9D0F1* / Kinetochore *  / complex
 ENSDARG00000034624 nuf2 / Q7ZW63 / NUF2, NDC80 kinetochore complex component, homolog / Q99P69* / Q9BZD4* / NUF2, NDC80 kinetochore complex component* / Mus musculus NUF2, NDC80 kinetochore complex component ...  / complex
 ENSDARG00000093622 spc24 / Q503N2 / SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) / Q9D083* / Q8NBT2* / Kinetochore protein Spc24 * / SPC24, NDC80 kinetochore complex component*  / complex
 ENSDARG00000077822 si:dkey-6i22.5 / PMF1* / Q6P1K2* / Q9CPV5* / PMF1-BGLAP* / PMF1-BGLAP readthrough* / polyamine modulated factor 1*  / complex
 ENSDARG00000078433 spc25 / SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) / Q9HBM1* / Q3UA16* / Kinetochore protein Spc25 * / SPC25, NDC80 kinetochore complex component*  / complex
 ENSDARG00000089922 dsn1 / DSN1 homolog, MIS12 kinetochore complex component / Q9H410*  / complex






 

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