ENSMUSG00000062510


Mus musculus

Features
Gene ID: ENSMUSG00000062510
  
Biological name :Nsl1
  
Synonyms : Nsl1 / NSL1, MIS12 kinetochore complex component
  
Possible biological names infered from orthology : Q96IY1
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: H6
Gene start: 191063012
Gene end: 191086474
  
Corresponding Affymetrix probe sets: 10352709 (MoGene1.0st)   1447705_at (Mouse Genome 430 2.0 Array)   1455852_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000076220
Ensembl peptide - ENSMUSP00000115289
Ensembl peptide - ENSMUSP00000077380
NCBI entrez gene - 381318     See in Manteia.
MGI - MGI:2685830
RefSeq - XM_017321425
RefSeq - NM_198654
RefSeq - XM_006497181
RefSeq - XM_011238922
RefSeq Peptide - NP_941056
swissprot - D3Z4S2
swissprot - E9Q3W6
swissprot - E9QME3
Ensembl - ENSMUSG00000062510
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nsl1ENSDARG00000024471Danio rerio
 NSL1ENSGALG00000009814Gallus gallus
 NSL1ENSG00000117697Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013950  Kinetochore Mis14/Nsl1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000070 mitotic sister chromatid segregation IEA
 cellular_componentGO:0000444 MIS12/MIND type complex IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0016607 nuclear speck IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000027326 Knl1 / Q66JQ7 / Kinetochore scaffold 1 / Q8NG31*  / complex
 ENSMUSG00000005233 Spc25 / Q3UA16 / Kinetochore protein Spc25 / Q9HBM1* / SPC25, NDC80 kinetochore complex component*  / complex
 ENSMUSG00000040599 Mis12 / Q9CY25 / MIS12, kinetochore complex component / Q9H081*  / complex
 ENSMUSG00000074476 Spc24 / Q9D083 / Kinetochore protein Spc24 / Q8NBT2* / SPC24, NDC80 kinetochore complex component*  / complex
 ENSMUSG00000028066 Pmf1 / Q9CPV5 / Polyamine-modulated factor 1 / Q6P1K2*  / complex
 ENSMUSG00000026683 Nuf2 / Q99P69 / Mus musculus NUF2, NDC80 kinetochore complex component (Nuf2), transcript variant 2, mRNA. / Q9BZD4* / NUF2, NDC80 kinetochore complex component*  / complex
 ENSMUSG00000024056 Ndc80 / Q9D0F1 / Kinetochore / O14777* / NDC80, kinetochore complex component*  / complex
 ENSMUSG00000027635 Dsn1 / Q9CYC5 / Kinetochore-associated / Q9H410* / DSN1 homolog, MIS12 kinetochore complex component*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr