ENSMUSG00000027635


Mus musculus

Features
Gene ID: ENSMUSG00000027635
  
Biological name :Dsn1
  
Synonyms : Dsn1 / Kinetochore-associated / Q9CYC5
  
Possible biological names infered from orthology : DSN1 homolog, MIS12 kinetochore complex component / Q9H410
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H1
Gene start: 156995265
Gene end: 157007154
  
Corresponding Affymetrix probe sets: 10489078 (MoGene1.0st)   1417139_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000099419
Ensembl peptide - ENSMUSP00000122593
Ensembl peptide - ENSMUSP00000122524
Ensembl peptide - ENSMUSP00000120354
Ensembl peptide - ENSMUSP00000099418
NCBI entrez gene - 66934     See in Manteia.
MGI - MGI:1914184
RefSeq - NM_025853
RefSeq Peptide - NP_080129
swissprot - B0QZT4
swissprot - A2ACV5
swissprot - B0QZT5
swissprot - Q9CYC5
Ensembl - ENSMUSG00000027635
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dsn1ENSDARG00000089922Danio rerio
 DSN1ENSG00000149636Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013218  Kinetochore-associated protein Dsn1/Mis13


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000070 mitotic sister chromatid segregation IBA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051456 attachment of spindle microtubules to kinetochore involved in meiotic sister chromatid segregation IBA
 cellular_componentGO:0000444 MIS12/MIND type complex IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore ISO
 cellular_componentGO:0000818 nuclear MIS12/MIND complex IBA
 cellular_componentGO:0000922 spindle pole IBA
 cellular_componentGO:0000941 condensed nuclear chromosome inner kinetochore IBA
 cellular_componentGO:0001650 fibrillar center IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016604 nuclear body IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Neutrophil degranulation
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000027326 Knl1 / Q66JQ7 / Kinetochore scaffold 1 / Q8NG31*  / complex
 ENSMUSG00000062510 Nsl1 / NSL1, MIS12 kinetochore complex component / Q96IY1*  / complex
 ENSMUSG00000026683 Nuf2 / Q99P69 / Mus musculus NUF2, NDC80 kinetochore complex component (Nuf2), transcript variant 2, mRNA. / Q9BZD4* / NUF2, NDC80 kinetochore complex component*  / complex
 ENSMUSG00000028066 Pmf1 / Q9CPV5 / Polyamine-modulated factor 1 / Q6P1K2*  / complex
 ENSMUSG00000040599 Mis12 / Q9CY25 / MIS12, kinetochore complex component / Q9H081*  / complex
 ENSMUSG00000024056 Ndc80 / Q9D0F1 / Kinetochore / O14777* / NDC80, kinetochore complex component*  / complex
 ENSMUSG00000005233 Spc25 / Q3UA16 / Kinetochore protein Spc25 / Q9HBM1* / SPC25, NDC80 kinetochore complex component*  / complex
 ENSMUSG00000074476 Spc24 / Q9D083 / Kinetochore protein Spc24 / Q8NBT2* / SPC24, NDC80 kinetochore complex component*  / complex






 

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