ENSMUSG00000028066


Mus musculus

Features
Gene ID: ENSMUSG00000028066
  
Biological name :Pmf1
  
Synonyms : Pmf1 / Polyamine-modulated factor 1 / Q9CPV5
  
Possible biological names infered from orthology : Q6P1K2
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F1
Gene start: 88394143
Gene end: 88410331
  
Corresponding Affymetrix probe sets: 10499366 (MoGene1.0st)   1416707_a_at (Mouse Genome 430 2.0 Array)   1438173_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000062420
Ensembl peptide - ENSMUSP00000141229
Ensembl peptide - ENSMUSP00000141696
NCBI entrez gene - 67037     See in Manteia.
MGI - MGI:1914287
RefSeq - XM_011240202
RefSeq - NM_001310605
RefSeq - NM_025928
RefSeq Peptide - NP_001297534
RefSeq Peptide - NP_080204
swissprot - Q9CPV5
swissprot - A0A0A6YVR2
Ensembl - ENSMUSG00000028066
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-6i22.5ENSDARG00000077822Danio rerio
 PMF1ENSG00000160783Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007128  Nuclear MIS12/MIND complex subunit PMF1/Nnf1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007059 chromosome segregation ISS
 biological_processGO:0051301 cell division IEA
 biological_processGO:1903506 regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0000444 MIS12/MIND type complex IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043522 leucine zipper domain binding IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000027326 Knl1 / Q66JQ7 / Kinetochore scaffold 1 / Q8NG31*  / complex
 ENSMUSG00000074476 Spc24 / Q9D083 / Kinetochore protein Spc24 / Q8NBT2* / SPC24, NDC80 kinetochore complex component*  / complex
 ENSMUSG00000024056 Ndc80 / Q9D0F1 / Kinetochore / O14777* / NDC80, kinetochore complex component*  / complex
 ENSMUSG00000040599 Mis12 / Q9CY25 / MIS12, kinetochore complex component / Q9H081*  / complex
 ENSMUSG00000026683 Nuf2 / Q99P69 / Mus musculus NUF2, NDC80 kinetochore complex component (Nuf2), transcript variant 2, mRNA. / Q9BZD4* / NUF2, NDC80 kinetochore complex component*  / complex
 ENSMUSG00000005233 Spc25 / Q3UA16 / Kinetochore protein Spc25 / Q9HBM1* / SPC25, NDC80 kinetochore complex component*  / complex
 ENSMUSG00000062510 Nsl1 / NSL1, MIS12 kinetochore complex component / Q96IY1*  / complex
 ENSMUSG00000027635 Dsn1 / Q9CYC5 / Kinetochore-associated / Q9H410* / DSN1 homolog, MIS12 kinetochore complex component*  / complex






 

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