ENSG00000160783


Homo sapiens

Features
Gene ID: ENSG00000160783
  
Biological name :PMF1
  
Synonyms : PMF1 / polyamine modulated factor 1 / Q6P1K2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q22
Gene start: 156212993
Gene end: 156240042
  
Corresponding Affymetrix probe sets: 202337_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357260
Ensembl peptide - ENSP00000476760
Ensembl peptide - ENSP00000476770
Ensembl peptide - ENSP00000357256
Ensembl peptide - ENSP00000357262
NCBI entrez gene - 11243     See in Manteia.
OMIM - 609176
RefSeq - NM_001199654
RefSeq - NM_001199653
RefSeq - NM_007221
RefSeq Peptide - NP_001186582
RefSeq Peptide - NP_001186583
RefSeq Peptide - NP_009152
swissprot - Q6P1K2
swissprot - V9GYH6
swissprot - V9GYI0
Ensembl - ENSG00000160783
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-6i22.5ENSDARG00000077822Danio rerio
 Pmf1ENSMUSG00000028066Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PMF1-BGLAP / PMF1-BGLAP readthroughENSG0000026023851


Protein motifs (from Interpro)
Interpro ID Name
 IPR007128  Nuclear MIS12/MIND complex subunit PMF1/Nnf1
 IPR027267  AH/BAR domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007059 chromosome segregation IMP
 biological_processGO:0007062 sister chromatid cohesion TAS
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000444 MIS12/MIND type complex IDA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005667 transcription factor complex TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0003713 transcription coactivator activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043522 leucine zipper domain binding IPI


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000137812 KNL1 / Q8NG31 / kinetochore scaffold 1  / complex
 ENSG00000167842 MIS12 / Q9H081 / MIS12, kinetochore complex component  / complex
 ENSG00000152253 SPC25 / Q9HBM1 / SPC25, NDC80 kinetochore complex component  / complex
 ENSG00000080986 NDC80 / O14777 / NDC80, kinetochore complex component  / complex
 ENSG00000161888 SPC24 / Q8NBT2 / SPC24, NDC80 kinetochore complex component  / complex
 ENSG00000143228 NUF2 / Q9BZD4 / NUF2, NDC80 kinetochore complex component  / complex
 ENSG00000149636 DSN1 / Q9H410 / DSN1 homolog, MIS12 kinetochore complex component  / complex
 ENSG00000117697 NSL1 / Q96IY1 / NSL1, MIS12 kinetochore complex component  / complex






 

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