ENSG00000143228


Homo sapiens

Features
Gene ID: ENSG00000143228
  
Biological name :NUF2
  
Synonyms : NUF2 / NUF2, NDC80 kinetochore complex component / Q9BZD4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q23.3
Gene start: 163266576
Gene end: 163355764
  
Corresponding Affymetrix probe sets: 223381_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000271452
Ensembl peptide - ENSP00000356875
Ensembl peptide - ENSP00000436888
Ensembl peptide - ENSP00000436473
Ensembl peptide - ENSP00000433533
Ensembl peptide - ENSP00000403252
Ensembl peptide - ENSP00000392652
NCBI entrez gene - 83540     See in Manteia.
OMIM - 611772
RefSeq - XM_011510036
RefSeq - NM_031423
RefSeq - NM_145697
RefSeq Peptide - NP_113611
RefSeq Peptide - NP_663735
swissprot - Q9BZD4
swissprot - E9PQC4
swissprot - E9PP32
swissprot - B1AQT4
swissprot - E9PKH1
swissprot - B1AQT3
Ensembl - ENSG00000143228
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nuf2ENSDARG00000034624Danio rerio
 NUF2ENSGALG00000003438Gallus gallus
 Nuf2ENSMUSG00000026683Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005549  Kinetochore protein Nuf2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007059 chromosome segregation NAS
 biological_processGO:0007062 sister chromatid cohesion TAS
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000775 chromosome, centromeric region NAS
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0031262 Ndc80 complex IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000080986 NDC80 / O14777 / NDC80, kinetochore complex component  / complex
 ENSG00000152253 SPC25 / Q9HBM1 / SPC25, NDC80 kinetochore complex component  / complex
 ENSG00000137812 KNL1 / Q8NG31 / kinetochore scaffold 1  / complex
 ENSG00000160783 PMF1 / Q6P1K2 / polyamine modulated factor 1  / complex
 ENSG00000149636 DSN1 / Q9H410 / DSN1 homolog, MIS12 kinetochore complex component  / complex
 ENSG00000117697 NSL1 / Q96IY1 / NSL1, MIS12 kinetochore complex component  / complex
 ENSG00000167842 MIS12 / Q9H081 / MIS12, kinetochore complex component  / complex
 ENSG00000161888 SPC24 / Q8NBT2 / SPC24, NDC80 kinetochore complex component  / complex






 

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