ENSMUSG00000074476


Mus musculus

Features
Gene ID: ENSMUSG00000074476
  
Biological name :Spc24
  
Synonyms : Kinetochore protein Spc24 / Q9D083 / Spc24
  
Possible biological names infered from orthology : Q8NBT2 / SPC24, NDC80 kinetochore complex component
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A3
Gene start: 21755442
Gene end: 21760303
  
Corresponding Affymetrix probe sets: 10591556 (MoGene1.0st)   1431087_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000149956
Ensembl peptide - ENSMUSP00000151082
Ensembl peptide - ENSMUSP00000150475
Ensembl peptide - ENSMUSP00000096541
NCBI entrez gene - 67629     See in Manteia.
MGI - MGI:1914879
RefSeq - NM_026282
RefSeq - XM_011242588
RefSeq Peptide - NP_001344260
RefSeq Peptide - NP_080558
swissprot - A0A1L1SSK2
swissprot - Q9D083
swissprot - A0A1L1SV84
Ensembl - ENSMUSG00000074476
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spc24ENSDARG00000093622Danio rerio
 SPC24ENSG00000161888Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013252  Kinetochore-Ndc80 subunit Spc24


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0031262 Ndc80 complex ISO
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000027326 Knl1 / Q66JQ7 / Kinetochore scaffold 1 / Q8NG31*  / complex
 ENSMUSG00000040599 Mis12 / Q9CY25 / MIS12, kinetochore complex component / Q9H081*  / complex
 ENSMUSG00000028066 Pmf1 / Q9CPV5 / Polyamine-modulated factor 1 / Q6P1K2*  / complex
 ENSMUSG00000062510 Nsl1 / NSL1, MIS12 kinetochore complex component / Q96IY1*  / complex
 ENSMUSG00000026683 Nuf2 / Q99P69 / Mus musculus NUF2, NDC80 kinetochore complex component (Nuf2), transcript variant 2, mRNA. / Q9BZD4* / NUF2, NDC80 kinetochore complex component*  / complex
 ENSMUSG00000005233 Spc25 / Q3UA16 / Kinetochore protein Spc25 / Q9HBM1* / SPC25, NDC80 kinetochore complex component*  / complex
 ENSMUSG00000024056 Ndc80 / Q9D0F1 / Kinetochore / O14777* / NDC80, kinetochore complex component*  / complex
 ENSMUSG00000027635 Dsn1 / Q9CYC5 / Kinetochore-associated / Q9H410* / DSN1 homolog, MIS12 kinetochore complex component*  / complex






 

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