ENSMUSG00000005233


Mus musculus

Features
Gene ID: ENSMUSG00000005233
  
Biological name :Spc25
  
Synonyms : Kinetochore protein Spc25 / Q3UA16 / Spc25
  
Possible biological names infered from orthology : Q9HBM1 / SPC25, NDC80 kinetochore complex component
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: C2
Gene start: 69193895
Gene end: 69206194
  
Corresponding Affymetrix probe sets: 10483401 (MoGene1.0st)   1424118_a_at (Mouse Genome 430 2.0 Array)   1453815_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000120999
Ensembl peptide - ENSMUSP00000117415
Ensembl peptide - ENSMUSP00000128039
Ensembl peptide - ENSMUSP00000120142
Ensembl peptide - ENSMUSP00000005365
Ensembl peptide - ENSMUSP00000107939
NCBI entrez gene - 66442     See in Manteia.
MGI - MGI:1913692
RefSeq - XM_006500003
RefSeq - NM_001199123
RefSeq - NM_001199124
RefSeq - NM_001305800
RefSeq - NM_025565
RefSeq Peptide - NP_001186052
RefSeq Peptide - NP_001186053
RefSeq Peptide - NP_001292729
RefSeq Peptide - NP_079841
swissprot - A2AUT3
swissprot - A2AUT4
swissprot - Q3UA16
swissprot - A2AUT1
Ensembl - ENSMUSG00000005233
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spc25ENSDARG00000078433Danio rerio
 SPC25ENSGALG00000010900Gallus gallus
 SPC25ENSG00000152253Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013255  Chromosome segregation protein Spc25


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007052 mitotic spindle organization ISS
 biological_processGO:0007059 chromosome segregation ISO
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0031262 Ndc80 complex ISO
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000026683 Nuf2 / Q99P69 / Mus musculus NUF2, NDC80 kinetochore complex component (Nuf2), transcript variant 2, mRNA. / Q9BZD4* / NUF2, NDC80 kinetochore complex component*  / complex
 ENSMUSG00000024056 Ndc80 / Q9D0F1 / Kinetochore / O14777* / NDC80, kinetochore complex component*  / complex
 ENSMUSG00000027326 Knl1 / Q66JQ7 / Kinetochore scaffold 1 / Q8NG31*  / complex
 ENSMUSG00000040599 Mis12 / Q9CY25 / MIS12, kinetochore complex component / Q9H081*  / complex
 ENSMUSG00000028066 Pmf1 / Q9CPV5 / Polyamine-modulated factor 1 / Q6P1K2*  / complex
 ENSMUSG00000062510 Nsl1 / NSL1, MIS12 kinetochore complex component / Q96IY1*  / complex
 ENSMUSG00000074476 Spc24 / Q9D083 / Kinetochore protein Spc24 / Q8NBT2* / SPC24, NDC80 kinetochore complex component*  / complex
 ENSMUSG00000027635 Dsn1 / Q9CYC5 / Kinetochore-associated / Q9H410* / DSN1 homolog, MIS12 kinetochore complex component*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr