ENSGALG00000010900


Gallus gallus

Features
Gene ID: ENSGALG00000010900
  
Biological name :SPC25
  
Synonyms : SPC25 / SPC25, NDC80 kinetochore complex component
  
Possible biological names infered from orthology : Kinetochore protein Spc25 / Q3UA16 / Q9HBM1
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 19023492
Gene end: 19027011
  
Corresponding Affymetrix probe sets: Gga.12203.1.S1_at (Chicken Array)   Gga.6047.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000017703
Ensembl peptide - ENSGALP00000063674
NCBI entrez gene - 424172     See in Manteia.
RefSeq - NM_001277857
RefSeq Peptide - NP_001264786
swissprot - E1C4Y2
swissprot - A0A1L1RXV1
Ensembl - ENSGALG00000010900
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spc25ENSDARG00000078433Danio rerio
 SPC25ENSG00000152253Homo sapiens
 Spc25ENSMUSG00000005233Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013255  Chromosome segregation protein Spc25


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007052 mitotic spindle organization IEA
 biological_processGO:0007059 chromosome segregation IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0031262 Ndc80 complex IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000014801 NDC80 / Q76I89 / Kinetochore protein NDC80 homolog / Q9D0F1* / O14777* / Kinetochore * / NDC80, kinetochore complex component*  / complex
 ENSGALG00000003438 NUF2 / NUF2, NDC80 kinetochore complex component / Q99P69* / Q9BZD4* / Mus musculus NUF2, NDC80 kinetochore complex component (Nuf2), transcript variant 2, mRNA.*  / complex
 ENSGALG00000009814 NSL1 / NSL1, MIS12 kinetochore complex component / Q96IY1*  / complex






 

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contact: otassy@igbmc.fr