ENSGALG00000014801


Gallus gallus

Features
Gene ID: ENSGALG00000014801
  
Biological name :NDC80
  
Synonyms : Kinetochore protein NDC80 homolog / NDC80 / Q76I89
  
Possible biological names infered from orthology : Kinetochore / NDC80, kinetochore complex component / O14777 / Q9D0F1
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 101458366
Gene end: 101477125
  
Corresponding Affymetrix probe sets: Gga.9350.1.S1_s_at (Chicken Array)   GgaAffx.11749.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000023851
Ensembl peptide - ENSGALP00000062448
Ensembl peptide - ENSGALP00000060687
Ensembl peptide - ENSGALP00000050416
NCBI entrez gene - 395134     See in Manteia.
RefSeq - NM_204477
RefSeq - XM_015277933
RefSeq Peptide - NP_989808
swissprot - A0A1D5PCC8
swissprot - A0A1L1RUF0
swissprot - Q76I89
swissprot - A0A1L1RPI4
Ensembl - ENSGALG00000014801
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ndc80ENSDARG00000071694Danio rerio
 NDC80ENSG00000080986Homo sapiens
 Ndc80ENSMUSG00000024056Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005550  Kinetochore protein Ndc80


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000132 establishment of mitotic spindle orientation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007052 mitotic spindle organization IEA
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0008608 attachment of spindle microtubules to kinetochore IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051310 metaphase plate congression IEA
 biological_processGO:0051315 attachment of mitotic spindle microtubules to kinetochore IEA
 biological_processGO:0051383 kinetochore organization IEA
 biological_processGO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint IEA
 biological_processGO:1905342 positive regulation of protein localization to kinetochore IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore ISS
 cellular_componentGO:0000777 condensed chromosome kinetochore ISS
 cellular_componentGO:0000778 condensed nuclear chromosome kinetochore IBA
 cellular_componentGO:0000942 condensed nuclear chromosome outer kinetochore IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0031262 Ndc80 complex IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000010900 SPC25 / SPC25, NDC80 kinetochore complex component / Q3UA16* / Q9HBM1* / Kinetochore protein Spc25 *  / complex
 ENSGALG00000009814 NSL1 / NSL1, MIS12 kinetochore complex component / Q96IY1*  / complex
 ENSGALG00000003438 NUF2 / NUF2, NDC80 kinetochore complex component / Q99P69* / Q9BZD4* / Mus musculus NUF2, NDC80 kinetochore complex component (Nuf2), transcript variant 2, mRNA.*  / complex






 

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