ENSDARG00000036074


Danio rerio

Features
Gene ID: ENSDARG00000036074
  
Biological name :cebpa
  
Synonyms : CCAAT/enhancer binding protein (C/EBP), alpha / cebpa
  
Possible biological names infered from orthology : CCAAT/enhancer binding protein alpha / P49715 / P53566
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 38084986
Gene end: 38087865
  
Corresponding Affymetrix probe sets: Dr.12055.1.S1_at (Zebrafish Array)   NM_131885_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000052365
NCBI entrez gene - 140815     See in Manteia.
RefSeq - NM_131885
RefSeq Peptide - NP_571960
swissprot - Q8UVZ1
ZFIN ID - ZDB-GENE-020111-2
Ensembl - ENSDARG00000036074
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CEBPAENSGALG00000026525Gallus gallus
 CEBPAENSG00000245848Homo sapiens
 CebpaENSMUSG00000034957Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cebpb / CCAAT/enhancer binding protein (C/EBP), beta / P17676* / CCAAT/enhancer binding protein beta*ENSDARG0000004272529
cebpd / CCAAT/enhancer binding protein (C/EBP), delta / P49716* / CCAAT/enhancer binding protein delta*ENSDARG0000008730328
cebp1 / CCAAT/enhancer binding protein (C/EBP) 1ENSDARG0000010109617
cebpg / CCAAT/enhancer binding protein (C/EBP), gamma / P53567* / P53568* / CCAAT/enhancer binding protein gamma*ENSDARG0000003607314


Protein motifs (from Interpro)
Interpro ID Name
 IPR004827  Basic-leucine zipper domain
 IPR016468  CCAAT/enhancer-binding protein, chordates


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IMP
 biological_processGO:0002573 myeloid leukocyte differentiation IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0030223 neutrophil differentiation IGI
 biological_processGO:0035701 hematopoietic stem cell migration IMP
 biological_processGO:0060215 primitive hemopoiesis IMP
 biological_processGO:0060216 definitive hemopoiesis IGI
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain macrophage absent , abnormal
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 ZFA:0000123 liver liver decreased size , abnormal
liver decreased distribution , abnormal
liver cell proliferation increased occurrence , abnormal
liver apoptotic process increased process quality , abnormal
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 ZFA:0001094 whole organism whole organism increased amount , abnormal
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 ZFA:0005029 rostral blood island rostral blood island myeloid lineage restricted progenitor cell decreased distribution , abnormal
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 ZFA:0009049 mature neutrophil mature neutrophil decreased amount , exacerbated
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 ZFA:0009141 macrophage macrophage abnormal , abnormal
macrophage absent , abnormal
macrophage increased amount , abnormal
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 ZFA:0009327 neutrophil neutrophil absent , abnormal
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 ZFA:0009352 neutrophil progenitor cell neutrophil progenitor cell decreased amount , abnormal
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 ZFA:0009356 myeloid lineage restricted progenitor cell myeloid lineage restricted progenitor cell accumulation rostral blood island , abnormal
myeloid lineage restricted progenitor cell mitotic S phase arrested , abnormal
myeloid lineage restricted progenitor cell myeloid leukocyte migration decreased occurrence , abnormal
myeloid lineage restricted progenitor cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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