ENSDARG00000036232


Danio rerio

Features
Gene ID: ENSDARG00000036232
  
Biological name :trpm7
  
Synonyms : transient receptor potential cation channel, subfamily M, member 7 / trpm7
  
Possible biological names infered from orthology : Q923J1 / Q96QT4
  
Species: Danio rerio
  
Chr. number: 18
Strand: -1
Band:
Gene start: 113928
Gene end: 158541
  
Corresponding Affymetrix probe sets: Dr.2991.1.A1_at (Zebrafish Array)   Dr.2991.2.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000123915
Ensembl peptide - ENSDARP00000124806
Ensembl peptide - ENSDARP00000145809
Ensembl peptide - ENSDARP00000146646
swissprot - F8W297
swissprot - F8W4J6
ZFIN ID - ZDB-GENE-021115-2
Ensembl - ENSDARG00000036232
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TRPM7ENSGALG00000023451Gallus gallus
 TRPM7ENSG00000092439Homo sapiens
 Trpm7ENSMUSG00000027365Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
trpm6 / transient receptor potential cation channel, subfamily M, member 6 / Q9BX84*ENSDARG0000010345441
trpm3 / transient receptor potential cation channel, subfamily M, member 3 / Q9HCF6*ENSDARG0000003918138
trpm1b / transient receptor potential cation channel, subfamily M, member 1b / TRPM1* / Q7Z4N2* / transient receptor potential cation channel subfamily M member 1*ENSDARG0000010347633
trpm1a / transient receptor potential cation channel, subfamily M, member 1a / TRPM1* / Q2TV84* / Q7Z4N2* / transient receptor potential cation channel subfamily M member 1*ENSDARG0000001125932
trpm2 / transient receptor potential cation channel, subfamily M, member 2 / O94759* / Q91YD4*ENSDARG0000010164118
trpm4a / transient receptor potential cation channel, subfamily M, member 4a / TRPM4* / Q7TN37* / Q8TD43* / transient receptor potential cation channel subfamily M member 4*ENSDARG0000005999317
trpm4b.2 / transient receptor potential cation channel, subfamily M, member 4b, transient receptor potential cation channel, subfamily M, member 4b, tandem duplicate 2 / TRPM4* / Q8TD43* / ...ENSDARG0000006343516
si:ch211-173d10.1 / TRPM4* / Q7TN37* / Q8TD43* / transient receptor potential cation channel subfamily M member 4*ENSDARG0000006334716
trpm5 / transient receptor potential cation channel, subfamily M, member 5 / Q9JJH7* / Q9NZQ8*ENSDARG0000005979214
si:ch211-173d10.1 / TRPM4* / Q8TD43* / transient receptor potential cation channel subfamily M member 4*ENSDARG000001094429


Protein motifs (from Interpro)
Interpro ID Name
 IPR004166  MHCK/EF2 kinase
 IPR011009  Protein kinase-like domain superfamily
 IPR029601  Transient receptor potential cation channel subfamily M member 7
 IPR032415  TRPM, tetramerisation domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development IMP
 biological_processGO:0001503 ossification IMP
 biological_processGO:0002027 regulation of heart rate IMP
 biological_processGO:0003014 renal system process IMP
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006582 melanin metabolic process IMP
 biological_processGO:0006812 cation transport IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IMP
 biological_processGO:0010960 magnesium ion homeostasis IDA
 biological_processGO:0010961 cellular magnesium ion homeostasis IEA
 biological_processGO:0030318 melanocyte differentiation IMP
 biological_processGO:0031017 exocrine pancreas development IMP
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0046928 regulation of neurotransmitter secretion IMP
 biological_processGO:0048066 developmental pigmentation IMP
 biological_processGO:0050678 regulation of epithelial cell proliferation IMP
 biological_processGO:0050909 sensory perception of taste IEA
 biological_processGO:0051262 protein tetramerization IEA
 biological_processGO:0070838 divalent metal ion transport IDA
 biological_processGO:0072507 divalent inorganic cation homeostasis IMP
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005227 calcium activated cation channel activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
TRP channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000114 heart heart decreased functionality , abnormal
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 ZFA:0000126 centrum centrum composition , abnormal
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 ZFA:0000150 pronephric duct pronephric duct obstructed , abnormal
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 ZFA:0000158 urostyle urostyle composition , abnormal
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 ZFA:0000240 metapterygoid metapterygoid ossified , abnormal
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 ZFA:0000270 maxilla maxilla composition , abnormal
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 ZFA:0000282 sensory system sensory system quality , abnormal
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 ZFA:0000316 basihyal bone basihyal bone ossified , abnormal
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 ZFA:0000326 caudal vertebra caudal vertebra condensed , abnormal
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 ZFA:0000364 hypural hypural composition , abnormal
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 ZFA:0000368 integument integument decreased pigmentation , abnormal
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 ZFA:0000418 pretectum pretectum serotonergic neuron increased amount , abnormal
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 ZFA:0000434 skeletal system skeletal system quality , abnormal
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 ZFA:0000514 frontal bone frontal bone composition , abnormal
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 ZFA:0000519 hemal arch hemal arch composition , abnormal
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 ZFA:0000529 kidney kidney decreased functionality , abnormal
kidney calcified , abnormal
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 ZFA:0000561 parasphenoid parasphenoid composition , abnormal
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 ZFA:0000567 premaxilla premaxilla composition , abnormal
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 ZFA:0000578 ceratohyal bone ceratohyal bone ossified , abnormal
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 ZFA:0000621 quadrate quadrate ossified , abnormal
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 ZFA:0000627 epihyal epihyal ossified , abnormal
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 ZFA:0000656 ectopterygoid ectopterygoid composition , abnormal
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 ZFA:0000657 entopterygoid entopterygoid composition , abnormal
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 ZFA:0000660 epural epural composition , abnormal
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 ZFA:0000672 hyomandibula hyomandibula ossified , abnormal
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 ZFA:0000692 symplectic symplectic ossified , abnormal
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 ZFA:0001066 neural arch neural arch composition , abnormal
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 ZFA:0001094 whole organism whole organism shape , abnormal
whole organism decreased size , abnormal
whole organism movement behavioral quality , abnormal
whole organism decreased pigmentation , abnormal
whole organism movement quality , abnormal
Show

 ZFA:0001115 trunk trunk lacks all parts of type melanocyte , abnormal
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 ZFA:0001188 Weberian apparatus Weberian apparatus malformed , abnormal
Weberian apparatus condensed , abnormal
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 ZFA:0001190 Weberian vertebra Weberian vertebra condensed , abnormal
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 ZFA:0001200 corpuscles of Stannius corpuscles of Stannius physical object quality , abnormal
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 ZFA:0001237 ceratobranchial 1 bone ceratobranchial 1 bone ossified , abnormal
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 ZFA:0001240 ceratobranchial 4 bone ceratobranchial 4 bone ossified , abnormal
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 ZFA:0001241 ceratobranchial 3 bone ceratobranchial 3 bone ossified , abnormal
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 ZFA:0001242 ceratobranchial 2 bone ceratobranchial 2 bone ossified , abnormal
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 ZFA:0001249 exocrine pancreas exocrine pancreas hypoplastic , abnormal
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 ZFA:0001287 renal tubule renal tubule calcified , abnormal
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 ZFA:0001396 parapophysis/rib parapophysis/rib malformed , abnormal
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 ZFA:0001550 caudal fin lepidotrichium caudal fin lepidotrichium composition , abnormal
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 ZFA:0001559 vertebral column vertebral column kinked , abnormal
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 ZFA:0009045 epithelial cell of pancreas epithelial cell of pancreas decreased area , abnormal
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 ZFA:0009090 pigment cell pigment cell quality , abnormal
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 ZFA:0009091 melanocyte melanocyte morphology , abnormal
melanocyte irregular spatial pattern , abnormal
melanocyte colorless , abnormal
melanocyte regulation of membrane potential disrupted , abnormal
melanocyte decreased amount , abnormal
melanocyte intensity , abnormal
melanocyte low saturation , abnormal
melanocyte decreased size , abnormal
melanocyte malformed , abnormal
melanocyte necrotic , abnormal
melanocyte melanosome malformed , abnormal
melanocyte quality , abnormal
melanocyte melanosome aggregated , abnormal
melanocyte decreased pigmentation , abnormal
melanocyte spatial pattern , abnormal
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 ZFA:0009249 melanoblast melanoblast decreased pigmentation , abnormal
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 ZFA:0009277 acinar cell acinar cell decreased size , abnormal
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 ZFA:0009301 dopaminergic neuron dopaminergic neuron decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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