ENSG00000092439


Homo sapiens

Features
Gene ID: ENSG00000092439
  
Biological name :TRPM7
  
Synonyms : Q96QT4 / transient receptor potential cation channel subfamily M member 7 / TRPM7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q21.2
Gene start: 50552473
Gene end: 50686815
  
Corresponding Affymetrix probe sets: 223323_x_at (Human Genome U133 Plus 2.0 Array)   223324_s_at (Human Genome U133 Plus 2.0 Array)   231689_at (Human Genome U133 Plus 2.0 Array)   237884_x_at (Human Genome U133 Plus 2.0 Array)   239484_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000495860
Ensembl peptide - ENSP00000452873
Ensembl peptide - ENSP00000453277
Ensembl peptide - ENSP00000454066
Ensembl peptide - ENSP00000320239
NCBI entrez gene - 54822     See in Manteia.
OMIM - 605692
RefSeq - XM_017022355
RefSeq - NM_017672
RefSeq - XM_005254486
RefSeq - XM_017022350
RefSeq - XM_017022351
RefSeq - XM_017022352
RefSeq - XM_017022353
RefSeq - XM_017022354
RefSeq - NM_001301212
RefSeq Peptide - NP_001288141
RefSeq Peptide - NP_060142
swissprot - H0YNM0
swissprot - A0A0C4DGL2
swissprot - A0A024R5V1
swissprot - Q96QT4
swissprot - H0YLN8
Ensembl - ENSG00000092439
  
Related genetic diseases (OMIM): 105500 - {Amyotrophic lateral sclerosis-parkinsonism/dementia complex, susceptibility to}, 105500
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trpm7ENSDARG00000036232Danio rerio
 TRPM7ENSGALG00000023451Gallus gallus
 Trpm7ENSMUSG00000027365Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TRPM6 / Q9BX84 / transient receptor potential cation channel subfamily M member 6ENSG0000011912155
TRPM3 / Q9HCF6 / transient receptor potential cation channel subfamily M member 3ENSG0000008306744
TRPM1 / Q7Z4N2 / transient receptor potential cation channel subfamily M member 1ENSG0000013416040
TRPM2 / O94759 / transient receptor potential cation channel subfamily M member 2ENSG0000014218521
TRPM4 / Q8TD43 / transient receptor potential cation channel subfamily M member 4ENSG0000013052918
TRPM5 / Q9NZQ8 / transient receptor potential cation channel subfamily M member 5ENSG0000007098517
TRPM8 / Q7Z2W7 / transient receptor potential cation channel subfamily M member 8ENSG0000014448116


Protein motifs (from Interpro)
Interpro ID Name
 IPR004166  MHCK/EF2 kinase
 IPR005821  Ion transport domain
 IPR011009  Protein kinase-like domain superfamily
 IPR029601  Transient receptor potential cation channel subfamily M member 7
 IPR032415  TRPM, tetramerisation domain
 IPR037162  TRPM, tetramerisation domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0010961 cellular magnesium ion homeostasis IEA
 biological_processGO:0012501 programmed cell death IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016340 calcium-dependent cell-matrix adhesion IEA
 biological_processGO:0031032 actomyosin structure organization IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0051262 protein tetramerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070266 necroptotic process IMP
 biological_processGO:0070588 calcium ion transmembrane transport TAS
 cellular_componentGO:0001726 ruffle IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005262 calcium channel activity TAS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017022 myosin binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
TRP channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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