ENSDARG00000037140


Danio rerio

Features
Gene ID: ENSDARG00000037140
  
Biological name :pfkfb1
  
Synonyms : 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 / pfkfb1
  
Possible biological names infered from orthology : P16118 / P70266
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 26017227
Gene end: 26037969
  
Corresponding Affymetrix probe sets: Dr.7274.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000113716
Ensembl peptide - ENSDARP00000028010
NCBI entrez gene - 327453     See in Manteia.
RefSeq - NM_199808
RefSeq - XM_005162149
RefSeq Peptide - NP_956102
swissprot - Q803Y6
swissprot - A2AR70
ZFIN ID - ZDB-GENE-030131-5664
Ensembl - ENSDARG00000037140
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P16118ENSG00000158571Homo sapiens
 P70266ENSMUSG00000025271Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:dkey-96f10.1 / P16118* / P70266* / PFKFB1* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1*ENSDARG0000007445777
pfkfb4b / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b / PFKFB4* / Q6DTY7* / Q16877* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4*ENSDARG0000002907574
pfkfb4a / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a / PFKFB4* / Q6DTY7* / Q16877* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4*ENSDARG0000005554072
pfkfb2b / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b / PFKFB2* / O60825* / Gm29427* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2*ENSDARG0000000203767
pfkfb2a / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a / PFKFB2* / O60825* / Gm29427* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2*ENSDARG0000002384067
pfkfb3 / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 / Q16875*ENSDARG0000000195366


Protein motifs (from Interpro)
Interpro ID Name
 IPR001345  Phosphoglycerate/bisphosphoglycerate mutase, active site
 IPR003094  Fructose-2,6-bisphosphatase
 IPR013078  Histidine phosphatase superfamily, clade-1
 IPR013079  6-phosphofructo-2-kinase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR029033  Histidine phosphatase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006000 fructose metabolic process IEA
 biological_processGO:0006003 fructose 2,6-bisphosphate metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0046835 carbohydrate phosphorylation IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003873 6-phosphofructo-2-kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
Glycolysis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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