ENSDARG00000001953


Danio rerio

Features
Gene ID: ENSDARG00000001953
  
Biological name :pfkfb3
  
Synonyms : 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 / pfkfb3
  
Possible biological names infered from orthology : Q16875
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 25472505
Gene end: 25485404
  
Corresponding Affymetrix probe sets: Dr.7626.1.A1_at (Zebrafish Array)   Dr.7626.2.S1_at (Zebrafish Array)   NM_213397_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000130144
Ensembl peptide - ENSDARP00000041401
NCBI entrez gene - 554477     See in Manteia.
RefSeq - NM_213397
RefSeq Peptide - NP_998562
swissprot - A0A0R4IBD1
swissprot - Q6P951
ZFIN ID - ZDB-GENE-040426-2724
Ensembl - ENSDARG00000001953
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PFKFB3ENSGALG00000040369Gallus gallus
 PFKFB3ENSG00000170525Homo sapiens
 Pfkfb3ENSMUSG00000026773Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pfkfb2b / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b / PFKFB2* / O60825* / Gm29427* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2*ENSDARG0000000203764
pfkfb2a / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a / PFKFB2* / O60825* / Gm29427* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2*ENSDARG0000002384061
pfkfb4b / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b / PFKFB4* / Q6DTY7* / Q16877* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4*ENSDARG0000002907560
pfkfb4a / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a / PFKFB4* / Q6DTY7* / Q16877* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4*ENSDARG0000005554060
si:dkey-96f10.1 / P16118* / P70266* / PFKFB1* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1*ENSDARG0000007445757
pfkfb1 / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 / P16118* / P70266*ENSDARG0000003714056


Protein motifs (from Interpro)
Interpro ID Name
 IPR001345  Phosphoglycerate/bisphosphoglycerate mutase, active site
 IPR003094  Fructose-2,6-bisphosphatase
 IPR013078  Histidine phosphatase superfamily, clade-1
 IPR013079  6-phosphofructo-2-kinase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR029033  Histidine phosphatase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006000 fructose metabolic process IEA
 biological_processGO:0006003 fructose 2,6-bisphosphate metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0046835 carbohydrate phosphorylation IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003873 6-phosphofructo-2-kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
Glycolysis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000001953 pfkfb3 / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 / Q16875*  / complex






 

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