ENSDARG00000023840


Danio rerio

Features
Gene ID: ENSDARG00000023840
  
Biological name :pfkfb2a
  
Synonyms : 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a / pfkfb2a
  
Possible biological names infered from orthology : 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 / Gm29427 / O60825 / PFKFB2
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 42765700
Gene end: 42810664
  
Corresponding Affymetrix probe sets: Dr.24973.1.S1_at (Zebrafish Array)   NM_201008_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000093104
NCBI entrez gene - 393983     See in Manteia.
RefSeq - NM_201008
RefSeq Peptide - NP_957302
swissprot - F1R374
ZFIN ID - ZDB-GENE-040426-966
Ensembl - ENSDARG00000023840
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PFKFB2ENSGALG00000001117Gallus gallus
 O60825ENSG00000123836Homo sapiens
 Gm29427ENSMUSG00000101904Mus musculus
 Pfkfb2ENSMUSG00000026409Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pfkfb2b / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b / PFKFB2* / O60825* / Gm29427* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2*ENSDARG0000000203778
pfkfb3 / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 / Q16875*ENSDARG0000000195362
pfkfb4b / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b / PFKFB4* / Q6DTY7* / Q16877* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4*ENSDARG0000002907559
pfkfb4a / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a / PFKFB4* / Q6DTY7* / Q16877* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4*ENSDARG0000005554058
pfkfb1 / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 / P16118* / P70266*ENSDARG0000003714058
si:dkey-96f10.1 / P16118* / P70266* / PFKFB1* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1*ENSDARG0000007445756


Protein motifs (from Interpro)
Interpro ID Name
 IPR001345  Phosphoglycerate/bisphosphoglycerate mutase, active site
 IPR003094  Fructose-2,6-bisphosphatase
 IPR013078  Histidine phosphatase superfamily, clade-1
 IPR013079  6-phosphofructo-2-kinase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR029033  Histidine phosphatase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006000 fructose metabolic process IEA
 biological_processGO:0006003 fructose 2,6-bisphosphate metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0046835 carbohydrate phosphorylation IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003873 6-phosphofructo-2-kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Glycolysis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000023840 pfkfb2a / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a / PFKFB2* / O60825* / Gm29427* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2*  / complex
 ENSDARG00000002037 pfkfb2b / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b / PFKFB2* / O60825* / Gm29427* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2*  / complex






 

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