ENSDARG00000002037


Danio rerio

Features
Gene ID: ENSDARG00000002037
  
Biological name :pfkfb2b
  
Synonyms : 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b / pfkfb2b
  
Possible biological names infered from orthology : 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 / Gm29427 / O60825 / PFKFB2
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 18784847
Gene end: 18800299
  
Corresponding Affymetrix probe sets: Dr.7788.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000155272
Ensembl peptide - ENSDARP00000128572
Ensembl peptide - ENSDARP00000128619
Ensembl peptide - ENSDARP00000147179
Ensembl peptide - ENSDARP00000154266
NCBI entrez gene - 564852     See in Manteia.
RefSeq - XM_005155843
RefSeq - XM_021479800
swissprot - X1WEC1
swissprot - X1WEG8
ZFIN ID - ZDB-GENE-120222-1
Ensembl - ENSDARG00000002037
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PFKFB2ENSGALG00000001117Gallus gallus
 O60825ENSG00000123836Homo sapiens
 Gm29427ENSMUSG00000101904Mus musculus
 Pfkfb2ENSMUSG00000026409Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pfkfb2a / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a / PFKFB2* / O60825* / Gm29427* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2*ENSDARG0000002384075
pfkfb3 / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 / Q16875*ENSDARG0000000195363
pfkfb4a / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a / PFKFB4* / Q6DTY7* / Q16877* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4*ENSDARG0000005554057
pfkfb4b / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b / PFKFB4* / Q6DTY7* / Q16877* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4*ENSDARG0000002907557
pfkfb1 / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 / P16118* / P70266*ENSDARG0000003714056
si:dkey-96f10.1 / P16118* / P70266* / PFKFB1* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1*ENSDARG0000007445755


Protein motifs (from Interpro)
Interpro ID Name
 IPR001345  Phosphoglycerate/bisphosphoglycerate mutase, active site
 IPR003094  Fructose-2,6-bisphosphatase
 IPR013078  Histidine phosphatase superfamily, clade-1
 IPR013079  6-phosphofructo-2-kinase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR029033  Histidine phosphatase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006000 fructose metabolic process IEA
 biological_processGO:0006003 fructose 2,6-bisphosphate metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0046835 carbohydrate phosphorylation IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003873 6-phosphofructo-2-kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Glycolysis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000023840 pfkfb2a / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a / PFKFB2* / O60825* / Gm29427* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2*  / complex
 ENSDARG00000002037 pfkfb2b / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b / PFKFB2* / O60825* / Gm29427* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2*  / complex






 

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