ENSDARG00000037655


Danio rerio

Features
Gene ID: ENSDARG00000037655
  
Biological name :pls3
  
Synonyms : plastin 3 (T isoform) / pls3
  
Possible biological names infered from orthology : Mus musculus plastin 3 (T-isoform) (Pls3), transcript variant 4, mRNA. / P13797 / plastin 3 / Q99K51
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 13453130
Gene end: 13525458
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000054848
Ensembl peptide - ENSDARP00000132035
NCBI entrez gene - 436598     See in Manteia.
swissprot - A0A0R4IB94
swissprot - Q6DG81
ZFIN ID - ZDB-GENE-040718-10
Ensembl - ENSDARG00000037655
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLS3ENSGALG00000005930Gallus gallus
 PLS3ENSG00000102024Homo sapiens
 Pls3ENSMUSG00000016382Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lcp1 / lymphocyte cytosolic protein 1 (L-plastin) / P13796* / lymphocyte cytosolic protein 1*ENSDARG0000002318877
pls1 / plastin 1 (I isoform) / Q14651* / Q3V0K9* / plastin 1*ENSDARG0000003927267


Protein motifs (from Interpro)
Interpro ID Name
 IPR001589  Actinin-type actin-binding domain, conserved site
 IPR001715  Calponin homology domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008045 motor neuron axon guidance IMP
 biological_processGO:0030282 bone mineralization IMP
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IMP
 biological_processGO:0051017 actin filament bundle assembly IBA
 biological_processGO:0051639 actin filament network formation IBA
 biological_processGO:0051764 actin crosslink formation IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005884 actin filament IBA
 cellular_componentGO:0032432 actin filament bundle IBA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0051015 actin filament binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0000555 opercular flap opercular flap mineralized , abnormal
Show

 ZFA:0000737 cranium cranium malformed , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism anterior-posterior axis decreased length , abnormal
Show

 ZFA:0001115 trunk trunk anatomical axis bent , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved , abnormal
post-vent region decreased size , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage malformed , abnormal
Show

 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage malformed , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage malformed , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage absent , abnormal
Show

 ZFA:0005145 muscle muscle deformed , abnormal
Show

 ZFA:0009052 motor neuron motor neuron axon branchiness , abnormal
motor neuron growth cone increased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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