ENSDARG00000039757


Danio rerio

Features
Gene ID: ENSDARG00000039757
  
Biological name :mcfd2
  
Synonyms : mcfd2 / multiple coagulation factor deficiency 2 / prop1
  
Possible biological names infered from orthology : Multiple coagulation factor deficiency / Q8K5B2 / Q8NI22
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 8682176
Gene end: 8692860
  
Corresponding Affymetrix probe sets: Dr.26544.1.A1_at (Zebrafish Array)   Dr.4897.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000058105
Ensembl peptide - ENSDARP00000058106
NCBI entrez gene - 449676     See in Manteia.
swissprot - F1R786
swissprot - Q5XJ39
ZFIN ID - ZDB-GENE-041010-8
ZFIN ID - ZDB-GENE-081107-40
Ensembl - ENSDARG00000039757
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MCFD2ENSGALG00000010017Gallus gallus
 MCFD2ENSG00000180398Homo sapiens
 Mcfd2ENSMUSG00000024150Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0021984 adenohypophysis development IMP
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
Cargo concentration in the ER
Transport to the Golgi and subsequent modification


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000039757 mcfd2 / prop1 / multiple coagulation factor deficiency 2 / Q8K5B2* / Q8NI22* / Multiple coagulation factor deficiency *  / complex
 ENSDARG00000055705 f5 / coagulation factor V / O88783* / P12259* / Coagulation factor V Coagulation factor V heavy chain Coagulation factor V light chain*  / reaction / complex






 

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contact: otassy@igbmc.fr