ENSMUSG00000024150


Mus musculus

Features
Gene ID: ENSMUSG00000024150
  
Biological name :Mcfd2
  
Synonyms : Mcfd2 / Multiple coagulation factor deficiency / Q8K5B2
  
Possible biological names infered from orthology : multiple coagulation factor deficiency 2 / Q8NI22
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: E4
Gene start: 87254658
Gene end: 87265935
  
Corresponding Affymetrix probe sets: 10453436 (MoGene1.0st)   1424024_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114354
Ensembl peptide - ENSMUSP00000123352
Ensembl peptide - ENSMUSP00000121820
Ensembl peptide - ENSMUSP00000119856
Ensembl peptide - ENSMUSP00000117105
Ensembl peptide - ENSMUSP00000024963
NCBI entrez gene - 193813     See in Manteia.
MGI - MGI:2183439
RefSeq - XM_011246328
RefSeq - NM_139295
RefSeq - NM_176808
RefSeq - XM_006523900
RefSeq - XM_006523901
RefSeq Peptide - NP_647456
RefSeq Peptide - NP_789778
swissprot - D0EW11
swissprot - D3Z1G3
swissprot - Q8K5B2
swissprot - D3YVL4
swissprot - D3Z6A4
Ensembl - ENSMUSG00000024150
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mcfd2ENSDARG00000039757Danio rerio
 MCFD2ENSGALG00000010017Gallus gallus
 MCFD2ENSG00000180398Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0019752 carboxylic acid metabolic process ISO
 cellular_componentGO:0005576 extracellular region ISO
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
Cargo concentration in the ER
Transport to the Golgi and subsequent modification


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000041891 Lman1 / Q9D0F3 / Protein ERGIC-53 / P49257* / lectin, mannose binding 1*  / complex
 ENSMUSG00000024150 Mcfd2 / Q8K5B2 / Multiple coagulation factor deficiency / Q8NI22* / multiple coagulation factor deficiency 2*  / complex
 ENSMUSG00000026579 F5 / O88783 / Coagulation factor V Coagulation factor V heavy chain Coagulation factor V light chain / P12259* / coagulation factor V*  / complex / reaction
 ENSMUSG00000031196 F8 / Q06194 / Coagulation factor VIII / P00451*  / complex / reaction






 

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