ENSDARG00000055705


Danio rerio

Features
Gene ID: ENSDARG00000055705
  
Biological name :f5
  
Synonyms : coagulation factor V / f5
  
Possible biological names infered from orthology : Coagulation factor V Coagulation factor V heavy chain Coagulation factor V light chain / O88783 / P12259
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 34127005
Gene end: 34147996
  
Corresponding Affymetrix probe sets: Dr.18429.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000072528
Ensembl peptide - ENSDARP00000132592
NCBI entrez gene - 327320     See in Manteia.
RefSeq - NM_001328531
RefSeq Peptide - NP_001315460
swissprot - B7ZVT7
swissprot - A0A0R4ICY4
swissprot - Q90X47
ZFIN ID - ZDB-GENE-030131-5531
Ensembl - ENSDARG00000055705
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 F5ENSGALG00000029298Gallus gallus
 F5ENSG00000198734Homo sapiens
 F5ENSMUSG00000026579Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
f8 / coagulation factor VIII, procoagulant component / P00451* / Q06194* / coagulation factor VIII*ENSDARG0000010138527
hephl1a / hephaestin-like 1aENSDARG0000005923118
cp / ceruloplasminENSDARG0000001031218
hephl1b / hephaestin-like 1b / HEPH* / Q9BQS7* / Q9Z0Z4* / hephaestin*ENSDARG0000002640318
nrp2a / neuropilin 2aENSDARG000000965468
mfge8a / milk fat globule-EGF factor 8 protein aENSDARG000000153497
nrp2b / neuropilin 2bENSDARG000000384467
edil3a / EGF-like repeats and discoidin I-like domains 3a / EDIL3* / O35474* / O43854* / EGF like repeats and discoidin domains 3* / EGF-like repeat and discoidin I-like domain-containing protein 3 *ENSDARG000000934137
mfge8b / milk fat globule-EGF factor 8 protein bENSDARG000000458037
nrp1a / neuropilin 1a / NRP1* / O14786* / P97333* / neuropilin 1*ENSDARG000001021537
edil3b / EGF-like repeats and discoidin I-like domains 3b / EDIL3* / O35474* / O43854* / EGF like repeats and discoidin domains 3* / EGF-like repeat and discoidin I-like domain-containing protein 3 *ENSDARG000000608777
nrp1b / neuropilin 1bENSDARG000000272906
dcbld1 / discoidin, CUB and LCCL domain containing 1 / Q8N8Z6* / Q9D4J3* / Mus musculus discoidin, CUB and LCCL domain containing 1 (Dcbld1), transcript variant 2, mRNA.*ENSDARG000000159075
dcbld2 / discoidin, CUB and LCCL domain containing 2 / Q91ZV3* / Q96PD2* / Mus musculus discoidin, CUB and LCCL domain containing 2 (Dcbld2), transcript variant 2, mRNA.*ENSDARG000000621775
rs1a / retinoschisin 1a / RS1* / Q9Z1L4* / O15537* / retinoschisin 1* / retinoschisis (X-linked, juvenile) 1 (human)*ENSDARG000000272364
si:dkey-34d22.1ENSDARG000001031814


Protein motifs (from Interpro)
Interpro ID Name
 IPR000421  Coagulation factor 5/8 C-terminal domain
 IPR008972  Cupredoxin
 IPR008979  Galactose-binding-like domain superfamily
 IPR011707  Multicopper oxidase, type 3
 IPR024715  Coagulation factor 5/8-like
 IPR033138  Multicopper oxidases, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009617 response to bacterium IDA
 molecular_functionGO:0005507 copper ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Common Pathway of Fibrin Clot Formation
COPII-mediated vesicle transport
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Cargo concentration in the ER
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000036041 f2 / coagulation factor II (thrombin) / P00734* / P19221* / Prothrombin Activation peptide fragment 1 Activation peptide fragment 2 Thrombin light chain Thrombin heavy chain*  / reaction
 ENSDARG00000039757 mcfd2 / prop1 / multiple coagulation factor deficiency 2 / Q8K5B2* / Q8NI22* / Multiple coagulation factor deficiency *  / reaction / complex
 ENSDARG00000055705 f5 / coagulation factor V / O88783* / P12259* / Coagulation factor V Coagulation factor V heavy chain Coagulation factor V light chain*  / complex
 ENSDARG00000088581 f10 / coagulation factor X / O88947* / P00742* / Coagulation factor X Factor X light chain Factor X heavy chain Activated factor Xa heavy chain*  / reaction / complex






 

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