ENSDARG00000027290


Danio rerio

Features
Gene ID: ENSDARG00000027290
  
Biological name :nrp1b
  
Synonyms : neuropilin 1b / nrp1b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 43469241
Gene end: 43507278
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000089037
Ensembl peptide - ENSDARP00000120161
swissprot - A2BEM4
swissprot - F1QHA9
ZFIN ID - ZDB-GENE-040611-1
Ensembl - ENSDARG00000027290
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nrp1a / neuropilin 1a / NRP1* / O14786* / P97333* / neuropilin 1*ENSDARG0000010215360
nrp2b / neuropilin 2bENSDARG0000003844646
nrp2a / neuropilin 2aENSDARG0000009654646
f5 / coagulation factor V / O88783* / P12259* / Coagulation factor V Coagulation factor V heavy chain Coagulation factor V light chain*ENSDARG0000005570522
f8 / coagulation factor VIII, procoagulant component / P00451* / Q06194* / coagulation factor VIII*ENSDARG0000010138521
edil3a / EGF-like repeats and discoidin I-like domains 3a / EDIL3* / O35474* / O43854* / EGF like repeats and discoidin domains 3* / EGF-like repeat and discoidin I-like domain-containing protein 3 *ENSDARG0000009341318
mfge8b / milk fat globule-EGF factor 8 protein bENSDARG0000004580317
edil3b / EGF-like repeats and discoidin I-like domains 3b / EDIL3* / O35474* / O43854* / EGF like repeats and discoidin domains 3* / EGF-like repeat and discoidin I-like domain-containing protein 3 *ENSDARG0000006087717
mfge8a / milk fat globule-EGF factor 8 protein aENSDARG0000001534917
dcbld2 / discoidin, CUB and LCCL domain containing 2 / Q91ZV3* / Q96PD2* / Mus musculus discoidin, CUB and LCCL domain containing 2 (Dcbld2), transcript variant 2, mRNA.*ENSDARG0000006217715
dcbld1 / discoidin, CUB and LCCL domain containing 1 / Q8N8Z6* / Q9D4J3* / Mus musculus discoidin, CUB and LCCL domain containing 1 (Dcbld1), transcript variant 2, mRNA.*ENSDARG0000001590712
si:dkey-34d22.1ENSDARG0000010318111
hephl1b / hephaestin-like 1b / HEPH* / Q9BQS7* / Q9Z0Z4* / hephaestin*ENSDARG0000002640310
hephl1a / hephaestin-like 1aENSDARG0000005923110
cp / ceruloplasminENSDARG000000103129
rs1a / retinoschisin 1a / RS1* / Q9Z1L4* / O15537* / retinoschisin 1* / retinoschisis (X-linked, juvenile) 1 (human)*ENSDARG000000272366


Protein motifs (from Interpro)
Interpro ID Name
 IPR000421  Coagulation factor 5/8 C-terminal domain
 IPR000859  CUB domain
 IPR008979  Galactose-binding-like domain superfamily
 IPR027146  Neuropilin-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001570 vasculogenesis IMP
 biological_processGO:0001666 response to hypoxia IDA
 biological_processGO:0002040 sprouting angiogenesis IGI
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0009887 animal organ morphogenesis IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway IMP
 biological_processGO:0035767 endothelial cell chemotaxis IEA
 biological_processGO:0038084 vascular endothelial growth factor signaling pathway IEA
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway IEA
 biological_processGO:0061300 cerebellum vasculature development IMP
 biological_processGO:0071526 semaphorin-plexin signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005021 vascular endothelial growth factor-activated receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017154 semaphorin receptor activity IEA
 molecular_functionGO:0019838 growth factor binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000099 brain vasculature brain vasculature morphology , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel malformed , abnormal
intersegmental vessel angiogenesis process quality , abnormal
Show

 ZFA:0005010 mid cerebral vein mid cerebral vein absent , abnormal
mid cerebral vein decreased length , abnormal
Show

 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel malformed , abnormal
dorsal longitudinal anastomotic vessel aplastic , abnormal
Show

 ZFA:0009036 blood vessel endothelial cell blood vessel endothelial cell apoptotic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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