ENSDARG00000026403


Danio rerio

Features
Gene ID: ENSDARG00000026403
  
Biological name :hephl1b
  
Synonyms : hephaestin-like 1b / hephl1b
  
Possible biological names infered from orthology : HEPH / hephaestin / Q9BQS7 / Q9Z0Z4
  
Species: Danio rerio
  
Chr. number: 10
Strand: -1
Band:
Gene start: 24394023
Gene end: 24416471
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000120341
swissprot - F1QC68
ZFIN ID - ZDB-GENE-091204-388
Ensembl - ENSDARG00000026403
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HEPHENSG00000089472Homo sapiens
 HephENSMUSG00000031209Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hephl1a / hephaestin-like 1aENSDARG0000005923156
cp / ceruloplasminENSDARG0000001031249
f5 / coagulation factor V / O88783* / P12259* / Coagulation factor V Coagulation factor V heavy chain Coagulation factor V light chain*ENSDARG0000005570536
f8 / coagulation factor VIII, procoagulant component / P00451* / Q06194* / coagulation factor VIII*ENSDARG0000010138535
nrp2b / neuropilin 2bENSDARG000000384466
nrp2a / neuropilin 2aENSDARG000000965466
si:dkey-34d22.1ENSDARG000001031815
nrp1a / neuropilin 1a / NRP1* / O14786* / P97333* / neuropilin 1*ENSDARG000001021535
nrp1b / neuropilin 1bENSDARG000000272905
dcbld2 / discoidin, CUB and LCCL domain containing 2 / Q91ZV3* / Q96PD2* / Mus musculus discoidin, CUB and LCCL domain containing 2 (Dcbld2), transcript variant 2, mRNA.*ENSDARG000000621774
mfge8b / milk fat globule-EGF factor 8 protein bENSDARG000000458034
mfge8a / milk fat globule-EGF factor 8 protein aENSDARG000000153493
dcbld1 / discoidin, CUB and LCCL domain containing 1 / Q8N8Z6* / Q9D4J3* / Mus musculus discoidin, CUB and LCCL domain containing 1 (Dcbld1), transcript variant 2, mRNA.*ENSDARG000000159073
edil3b / EGF-like repeats and discoidin I-like domains 3b / EDIL3* / O35474* / O43854* / EGF like repeats and discoidin domains 3* / EGF-like repeat and discoidin I-like domain-containing protein 3 *ENSDARG000000608773
edil3a / EGF-like repeats and discoidin I-like domains 3a / EDIL3* / O35474* / O43854* / EGF like repeats and discoidin domains 3* / EGF-like repeat and discoidin I-like domain-containing protein 3 *ENSDARG000000934132
rs1a / retinoschisin 1a / RS1* / Q9Z1L4* / O15537* / retinoschisin 1* / retinoschisis (X-linked, juvenile) 1 (human)*ENSDARG000000272362


Protein motifs (from Interpro)
Interpro ID Name
 IPR002355  Multicopper oxidase, copper-binding site
 IPR008972  Cupredoxin
 IPR011706  Multicopper oxidase, type 2
 IPR011707  Multicopper oxidase, type 3
 IPR027154  Hephaestin
 IPR033138  Multicopper oxidases, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006826 iron ion transport IEA
 biological_processGO:0006879 cellular iron ion homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0005507 copper ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Metal ion SLC transporters
Iron uptake and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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