ENSDARG00000038446


Danio rerio

Features
Gene ID: ENSDARG00000038446
  
Biological name :nrp2b
  
Synonyms : neuropilin 2b / nrp2b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 14367570
Gene end: 14504834
  
Corresponding Affymetrix probe sets: Dr.18341.1.S1_at (Zebrafish Array)   NM_212966_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000056102
NCBI entrez gene - 405902     See in Manteia.
RefSeq - NM_212966
RefSeq Peptide - NP_998131
swissprot - B0S6D0
ZFIN ID - ZDB-GENE-040611-3
Ensembl - ENSDARG00000038446
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nrp2a / neuropilin 2aENSDARG0000009654674
nrp1a / neuropilin 1a / NRP1* / O14786* / P97333* / neuropilin 1*ENSDARG0000010215343
nrp1b / neuropilin 1bENSDARG0000002729027
f8 / coagulation factor VIII, procoagulant component / P00451* / Q06194* / coagulation factor VIII*ENSDARG0000010138517
f5 / coagulation factor V / O88783* / P12259* / Coagulation factor V Coagulation factor V heavy chain Coagulation factor V light chain*ENSDARG0000005570517
mfge8b / milk fat globule-EGF factor 8 protein bENSDARG0000004580315
edil3a / EGF-like repeats and discoidin I-like domains 3a / EDIL3* / O35474* / O43854* / EGF like repeats and discoidin domains 3* / EGF-like repeat and discoidin I-like domain-containing protein 3 *ENSDARG0000009341314
mfge8a / milk fat globule-EGF factor 8 protein aENSDARG0000001534914
edil3b / EGF-like repeats and discoidin I-like domains 3b / EDIL3* / O35474* / O43854* / EGF like repeats and discoidin domains 3* / EGF-like repeat and discoidin I-like domain-containing protein 3 *ENSDARG0000006087713
dcbld2 / discoidin, CUB and LCCL domain containing 2 / Q91ZV3* / Q96PD2* / Mus musculus discoidin, CUB and LCCL domain containing 2 (Dcbld2), transcript variant 2, mRNA.*ENSDARG0000006217711
dcbld1 / discoidin, CUB and LCCL domain containing 1 / Q8N8Z6* / Q9D4J3* / Mus musculus discoidin, CUB and LCCL domain containing 1 (Dcbld1), transcript variant 2, mRNA.*ENSDARG000000159079
si:dkey-34d22.1ENSDARG000001031818
hephl1b / hephaestin-like 1b / HEPH* / Q9BQS7* / Q9Z0Z4* / hephaestin*ENSDARG000000264037
hephl1a / hephaestin-like 1aENSDARG000000592316
cp / ceruloplasminENSDARG000000103126
rs1a / retinoschisin 1a / RS1* / Q9Z1L4* / O15537* / retinoschisin 1* / retinoschisis (X-linked, juvenile) 1 (human)*ENSDARG000000272366


Protein motifs (from Interpro)
Interpro ID Name
 IPR000421  Coagulation factor 5/8 C-terminal domain
 IPR000859  CUB domain
 IPR000998  MAM domain
 IPR008979  Galactose-binding-like domain superfamily
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR014648  Neuropilin
 IPR022579  Neuropilin, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001570 vasculogenesis IMP
 biological_processGO:0001755 neural crest cell migration IGI
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007411 axon guidance IMP
 biological_processGO:0007413 axonal fasciculation IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway IMP
 biological_processGO:0038084 vascular endothelial growth factor signaling pathway IEA
 biological_processGO:0071526 semaphorin-plexin signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005021 vascular endothelial growth factor-activated receptor activity IEA
 molecular_functionGO:0017154 semaphorin receptor activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000028 heart primordium heart primordium decreased size , abnormal
heart primordium decreased width , abnormal
heart primordium lacks parts or has fewer parts of type cardiac muscle cell , abnormal
Show

 ZFA:0001194 cranial neural crest cranial neural crest neural crest cell development disrupted , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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