ENSDARG00000039872


Danio rerio

Features
Gene ID: ENSDARG00000039872
  
Biological name :lamtor2
  
Synonyms : lamtor2 / late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
  
Possible biological names infered from orthology : Q9JHS3 / Q9Y2Q5 / Ragulator complex protein LAMTOR2
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 46684855
Gene end: 46691206
  
Corresponding Affymetrix probe sets: Dr.19588.1.S1_at (Zebrafish Array)   Dr.19588.2.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000058324
NCBI entrez gene - 445155     See in Manteia.
RefSeq - NM_001003549
RefSeq Peptide - NP_001003549
swissprot - F1R3H0
ZFIN ID - ZDB-GENE-040801-63
Ensembl - ENSDARG00000039872
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LAMTOR2ENSGALG00000029881Gallus gallus
 Q9Y2Q5ENSG00000116586Homo sapiens
 Q9JHS3ENSMUSG00000028062Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004942  Roadblock/LAMTOR2 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032008 positive regulation of TOR signaling IEA
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0032947 protein-containing complex scaffold activity IEA


Pathways (from Reactome)
Pathway description
Macroautophagy
mTOR signalling
mTORC1-mediated signalling
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
MAP2K and MAPK activation
Neutrophil degranulation
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000006609 map2k2a / mitogen-activated protein kinase kinase 2a / P36507* / MAP2K2* / Q63932* / AC011005.1* / mitogen-activated protein kinase kinase 2* / Mus musculus mitogen-activated protein kinase...  / complex / reaction
 ENSDARG00000017661 braf / B-Raf proto-oncogene, serine/threonine kinase / P15056* / P28028* / Serine/threonine-protein kinase B-raf *  / reaction / complex
 ENSDARG00000027552 mapk1 / mitogen-activated protein kinase 1 / P28482* / P63085* / Mus musculus mitogen-activated protein kinase 1 (Mapk1), transcript variant 3, mRNA.*  / reaction / complex
 ENSDARG00000070573 mapk3 / mitogen-activated protein kinase 3 / P27361* / Q63844*  / reaction / complex
 ENSDARG00000057075 lamtor3 / late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 / O88653* / Q9UHA4*  / complex






 

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