ENSDARG00000041665


Danio rerio

Features
Gene ID: ENSDARG00000041665
  
Biological name :mkrn1
  
Synonyms : makorin, ring finger protein, 1 / mkrn1 / Q4VBT5
  
Possible biological names infered from orthology : makorin ring finger protein 3 / MKRN3 / Probable E3 ubiquitin-protein ligase makorin-3 / Q13064 / Q60764 / Q9QXP6 / Q9UHC7
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 12292274
Gene end: 12307834
  
Corresponding Affymetrix probe sets: Dr.10442.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000125195
Ensembl peptide - ENSDARP00000125386
Ensembl peptide - ENSDARP00000061069
NCBI entrez gene - 170782     See in Manteia.
swissprot - B2GQH3
swissprot - H0WEB8
swissprot - H0WEV7
swissprot - Q4VBT5
ZFIN ID - ZDB-GENE-020213-1
Ensembl - ENSDARG00000041665
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MKRN1ENSGALG00000012852Gallus gallus
 MKRN1ENSG00000133606Homo sapiens
 MKRN3ENSG00000179455Homo sapiens
 Mkrn1ENSMUSG00000029922Mus musculus
 Mkrn3ENSMUSG00000070527Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mkrn2 / makorin, ring finger protein, 2 / Q9ERV1* / Q9H000* / Probable E3 ubiquitin-protein ligase makorin-2 *ENSDARG0000000763037
mkrn4 / makorin, ring finger protein, 4ENSDARG0000002829523


Protein motifs (from Interpro)
Interpro ID Name
 IPR000571  Zinc finger, CCCH-type
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR031644  E3 ubiquitin-protein ligase makorin 1, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
AKT phosphorylates targets in the cytosol
Regulation of PTEN stability and activity
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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