ENSDARG00000042641


Danio rerio

Features
Gene ID: ENSDARG00000042641
  
Biological name :cyp51
  
Synonyms : cyp51 / cytochrome P450, family 51 / Q1JPY5
  
Possible biological names infered from orthology : CYP51A1 / cytochrome P450 family 51 subfamily A member 1 / Lanosterol 14-alpha demethylase / Q16850 / Q8K0C4
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 598657
Gene end: 617246
  
Corresponding Affymetrix probe sets: Dr.1603.1.A1_at (Zebrafish Array)   Dr.1603.1.A1_x_at (Zebrafish Array)   DrAffx.2.81.A1_at (Zebrafish Array)   DrAffx.2.81.S1_at (Zebrafish Array)   NM_001001730_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000062550
NCBI entrez gene - 414331     See in Manteia.
RefSeq - NM_001001730
RefSeq Peptide - NP_001001730
swissprot - Q1JPY5
ZFIN ID - ZDB-GENE-040625-2
Ensembl - ENSDARG00000042641
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP51A1ENSGALG00000009365Gallus gallus
 Q16850ENSG00000001630Homo sapiens
 Cyp51ENSMUSG00000001467Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cyp26a1 / cytochrome P450, family 26, subfamily A, polypeptide 1 / O43174* / cytochrome P450 family 26 subfamily A member 1*ENSDARG0000003399920
cyp26c1 / cytochrome P450, family 26, subfamily C, polypeptide 1 / Q6V0L0* / cytochrome P450 family 26 subfamily C member 1*ENSDARG0000005602920
cyp26b1 / cytochrome P450, family 26, subfamily b, polypeptide 1 / Q811W2* / Q9NR63* / Cytochrome P450 26B1 * / cytochrome P450 family 26 subfamily B member 1*ENSDARG0000007712120


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002403  Cytochrome P450, E-class, group IV
 IPR017972  Cytochrome P450, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001878 response to yeast IDA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006694 steroid biosynthetic process IEA
 biological_processGO:0006695 cholesterol biosynthetic process IEA
 biological_processGO:0008202 steroid metabolic process IEA
 biological_processGO:0008203 cholesterol metabolic process IEA
 biological_processGO:0016126 sterol biosynthetic process IEA
 biological_processGO:0033488 cholesterol biosynthetic process via 24,25-dihydrolanosterol IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070988 demethylation IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008398 sterol 14-demethylase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Cholesterol biosynthesis
Endogenous sterols


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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