ENSDARG00000077121


Danio rerio

Features
Gene ID: ENSDARG00000077121
  
Biological name :cyp26b1
  
Synonyms : cyp26b1 / cytochrome P450, family 26, subfamily b, polypeptide 1
  
Possible biological names infered from orthology : Cytochrome P450 26B1 / cytochrome P450 family 26 subfamily B member 1 / Q811W2 / Q9NR63
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 25323742
Gene end: 25348597
  
Corresponding Affymetrix probe sets: Dr.180.1.A1_at (Zebrafish Array)   Dr.180.2.A1_at (Zebrafish Array)   Dr.26342.1.A1_at (Zebrafish Array)   DrAffx.2.62.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000101543
NCBI entrez gene - 324188     See in Manteia.
swissprot - A0A0R4I9F4
ZFIN ID - ZDB-GENE-030131-2908
Ensembl - ENSDARG00000077121
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP26B1ENSGALG00000016102Gallus gallus
 Q9NR63ENSG00000003137Homo sapiens
 Q811W2ENSMUSG00000063415Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cyp26c1 / cytochrome P450, family 26, subfamily C, polypeptide 1 / Q6V0L0* / cytochrome P450 family 26 subfamily C member 1*ENSDARG0000005602954
cyp26a1 / cytochrome P450, family 26, subfamily A, polypeptide 1 / O43174* / cytochrome P450 family 26 subfamily A member 1*ENSDARG0000003399939
cyp51 / Q1JPY5 / cytochrome P450, family 51 / Q8K0C4* / Q16850* / CYP51A1* / Lanosterol 14-alpha demethylase * / cytochrome P450 family 51 subfamily A member 1*ENSDARG0000004264119


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Vitamins
RA biosynthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain morphology , abnormal
hindbrain decreased size , abnormal
Show

 ZFA:0000051 otic vesicle otic vesicle decreased size , abnormal
Show

 ZFA:0000095 pharyngeal arch 3-7 skeleton pharyngeal arch 3-7 skeleton quality , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000126 centrum centrum ossified , abnormal
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 ZFA:0000170 basibranchial basibranchial malformed , abnormal
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 ZFA:0000250 opercle opercle increased size , abnormal
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 ZFA:0000364 hypural hypural malformed , abnormal
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 ZFA:0000514 frontal bone frontal bone decreased length , abnormal
frontal bone fused with parietal bone , abnormal
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 ZFA:0000547 mouth mouth decreased size , abnormal
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 ZFA:0000691 supraorbital bone supraorbital bone morphology , abnormal
Show

 ZFA:0000823 rhombomere 5 rhombomere 5 decreased width , abnormal
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 ZFA:0000948 rhombomere 3 rhombomere 3 decreased width , abnormal
Show

 ZFA:0001032 rhombomere 4 rhombomere 4 decreased size , abnormal
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 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001137 ventral tooth row ventral tooth row has extra parts of type ceratobranchial 5 tooth , abnormal
Show

 ZFA:0001161 pectoral fin pectoral fin decreased length , abnormal
pectoral fin malformed , abnormal
pectoral fin cartilage element mislocalised , abnormal
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 ZFA:0001189 vertebra vertebra fused with vertebra , abnormal
vertebra malformed , abnormal
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 ZFA:0001202 optic cup optic cup decreased size , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage aplastic , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton malformed , abnormal
mandibular arch skeleton decreased width , abnormal
Show

 ZFA:0001272 palatoquadrate arch palatoquadrate arch quality , abnormal
palatoquadrate arch protruding , abnormal
Show

 ZFA:0001273 ventral mandibular arch ventral mandibular arch protruding , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch malformed , abnormal
pharyngeal arch aplastic , abnormal
Show

 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage aplastic , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage malformed , abnormal
ceratohyal cartilage fused with ceratohyal cartilage , abnormal
Show

 ZFA:0001405 ethmoid cartilage ethmoid cartilage decreased size , abnormal
ethmoid cartilage malformed , abnormal
ethmoid cartilage hypoplastic , abnormal
ethmoid cartilage arrow-shaped , abnormal
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 ZFA:0001422 hyosymplectic cartilage hyosymplectic cartilage composition , abnormal
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 ZFA:0001423 parachordal cartilage parachordal cartilage malformed , abnormal
parachordal cartilage decreased size , abnormal
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 ZFA:0001456 pectoral fin endoskeletal disc pectoral fin endoskeletal disc hyperplastic , abnormal
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 ZFA:0001461 chondrocranium cartilage chondrocranium cartilage malformed , abnormal
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 ZFA:0001501 cartilage element cartilage element malformed , abnormal
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 ZFA:0001507 trabecula cranii trabecula cranii aplastic , abnormal
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 ZFA:0001510 basihyal cartilage basihyal cartilage malformed , abnormal
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 ZFA:0001514 bone element bone element malformed , abnormal
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 ZFA:0001555 epibranchial ganglion epibranchial ganglion disorganized , abnormal
epibranchial ganglion neuron decreased amount , abnormal
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 ZFA:0001559 vertebral column vertebral column ossified , abnormal
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 ZFA:0001580 neurocranium neurocranium malformed , abnormal
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 ZFA:0001613 pharyngeal arch 3-7 pharyngeal arch 3-7 malformed , abnormal
pharyngeal arch 3-7 aplastic , abnormal
Show

 ZFA:0005472 inter-frontal joint inter-frontal joint extracellular matrix decreased amount , abnormal
Show

 ZFA:0005607 inter-parietal joint inter-parietal joint open , abnormal
inter-parietal joint extracellular matrix decreased amount , abnormal
Show

 ZFA:0005608 frontal-parietal joint frontal-parietal joint closed , abnormal
frontal-parietal joint extracellular matrix decreased amount , abnormal
Show

 ZFA:0009031 osteoblast osteoblast star shaped , abnormal
osteoblast rough endoplasmic reticulum decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000045926 crabp1a / cellular retinoic acid binding protein 1a / CRABP1* / P29762* / P62965* / cellular retinoic acid binding protein 1*  / reaction
 ENSDARG00000035904 crabp1b / cellular retinoic acid binding protein 1b / CRABP1* / P29762* / P62965* / cellular retinoic acid binding protein 1*  / reaction






 

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