ENSDARG00000042644


Danio rerio

Features
Gene ID: ENSDARG00000042644
  
Biological name :sod2
  
Synonyms : sod2 / superoxide dismutase 2, mitochondrial
  
Possible biological names infered from orthology : P04179 / P09671 / superoxide dismutase 2
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 30937934
Gene end: 30947547
  
Corresponding Affymetrix probe sets: Dr.6314.1.S1_at (Zebrafish Array)   NM_199976_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000062555
NCBI entrez gene - 335799     See in Manteia.
RefSeq - NM_199976
RefSeq Peptide - NP_956270
swissprot - Q6P980
ZFIN ID - ZDB-GENE-030131-7742
Ensembl - ENSDARG00000042644
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SOD2ENSGALG00000011661Gallus gallus
 SOD2ENSG00000285441Homo sapiens
 SOD2ENSG00000112096Homo sapiens
 Sod2ENSMUSG00000006818Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001189  Manganese/iron superoxide dismutase
 IPR019831  Manganese/iron superoxide dismutase, N-terminal
 IPR019832  Manganese/iron superoxide dismutase, C-terminal
 IPR019833  Manganese/iron superoxide dismutase, binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001780 neutrophil homeostasis IMP
 biological_processGO:0006801 superoxide metabolic process IEA
 biological_processGO:0019430 removal of superoxide radicals IMP
 biological_processGO:0045087 innate immune response IMP
 biological_processGO:0046686 response to cadmium ion IEP
 biological_processGO:0051597 response to methylmercury IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0004784 superoxide dismutase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Transcriptional activation of mitochondrial biogenesis
Detoxification of Reactive Oxygen Species


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000094 blood island blood island macrophage decreased amount , abnormal
blood island neutrophil decreased amount , abnormal
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 ZFA:0000114 heart heart macrophage decreased amount , abnormal
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 ZFA:0001114 head head macrophage decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000035819 sirt3 / sirtuin 3 / Q8R104* / Q9NTG7*  / reaction
 ENSDARG00000042644 sod2 / superoxide dismutase 2, mitochondrial / P04179* / P09671* / superoxide dismutase 2*  / complex






 

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