ENSDARG00000042839


Danio rerio

Features
Gene ID: ENSDARG00000042839
  
Biological name :dph6
  
Synonyms : A2RV01 / diphthamine biosynthesis 6 / dph6
  
Possible biological names infered from orthology : Mus musculus diphthamine biosynthesis 6 (Dph6), transcript variant 3, mRNA. / Q7L8W6 / Q9CQ28
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 53156530
Gene end: 53197232
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000106089
Ensembl peptide - ENSDARP00000129691
Ensembl peptide - ENSDARP00000128574
NCBI entrez gene - 503603     See in Manteia.
RefSeq - NM_001013290
RefSeq Peptide - NP_001013308
swissprot - E7F9Q1
swissprot - A2RV01
swissprot - X1WEC3
ZFIN ID - ZDB-GENE-050227-15
Ensembl - ENSDARG00000042839
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DPH6ENSGALG00000020438Gallus gallus
 DPH6ENSG00000134146Homo sapiens
 Dph6ENSMUSG00000057147Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002761  Diphthamide synthase domain
 IPR006175  YjgF/YER057c/UK114 family
 IPR013813  Endoribonuclease L-PSP/chorismate mutase-like
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold
 IPR030662  Diphthine--ammonia ligase/Uncharacterised protein MJ0570


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0017178 diphthine-ammonia ligase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of diphthamide-EEF2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000035256 eef2l2 / eukaryotic translation elongation factor 2, like 2 / EEF2* / P58252* / P13639* / Elongation factor 2 * / eukaryotic translation elongation factor 2*  / reaction






 

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