ENSDARG00000042894


Danio rerio

Features
Gene ID: ENSDARG00000042894
  
Biological name :tyms
  
Synonyms : thymidylate synthetase / tyms
  
Possible biological names infered from orthology : P04818 / P07607 / thymidylate synthase
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 71535045
Gene end: 71541329
  
Corresponding Affymetrix probe sets: Dr.1047.1.S1_at (Zebrafish Array)   NM_131760_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000047068
NCBI entrez gene - 81540     See in Manteia.
RefSeq - NM_131760
RefSeq Peptide - NP_571835
swissprot - Q6P045
ZFIN ID - ZDB-GENE-040426-59
Ensembl - ENSDARG00000042894
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TYMSENSGALG00000014897Gallus gallus
 TYMSENSG00000176890Homo sapiens
 TymsENSMUSG00000025747Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000398  Thymidylate synthase
 IPR020940  Thymidylate synthase, active site
 IPR023451  Thymidylate synthase/dCMP hydroxymethylase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001654 eye development IMP
 biological_processGO:0006231 dTMP biosynthetic process IDA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0060041 retina development in camera-type eye IMP
 molecular_functionGO:0004799 thymidylate synthase activity IDA
 molecular_functionGO:0042083 5,10-methylenetetrahydrofolate-dependent methyltransferase activity IDA


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000035 lens lens protruding , abnormal
lens quality , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
eye pigmented , abnormal
Show

 ZFA:0000144 retinal pigmented epithelium retinal pigmented epithelium quality , abnormal
Show

 ZFA:0000152 retina retina quality , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0009091 melanocyte melanocyte quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000042894 tyms / thymidylate synthetase / P04818* / P07607* / thymidylate synthase*  / complex






 

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