ENSDARG00000043213


Danio rerio

Features
Gene ID: ENSDARG00000043213
  
Biological name :adam17a
  
Synonyms : adam17a / ADAM metallopeptidase domain 17a
  
Possible biological names infered from orthology : ADAM17 / ADAM metallopeptidase domain 17 / Disintegrin and metalloproteinase domain-containing protein 17 / P78536 / Q9Z0F8
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 35247497
Gene end: 35279422
  
Corresponding Affymetrix probe sets: Dr.2278.1.A1_at (Zebrafish Array)   NM_199673_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000063436
Ensembl peptide - ENSDARP00000147741
NCBI entrez gene - 324142     See in Manteia.
RefSeq - NM_199673
RefSeq Peptide - NP_955967
swissprot - Q5RFV3
ZFIN ID - ZDB-GENE-030131-2862
Ensembl - ENSDARG00000043213
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ADAM17ENSGALG00000016427Gallus gallus
 ADAM17ENSG00000151694Homo sapiens
 Adam17ENSMUSG00000052593Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
adam17b / ADAM metallopeptidase domain 17b / ADAM17* / P78536* / Q9Z0F8* / ADAM metallopeptidase domain 17* / Disintegrin and metalloproteinase domain-containing protein 17 *ENSDARG0000009309363
adam10a / ADAM metallopeptidase domain 10a / ADAM10* / O14672* / O35598* / ADAM metallopeptidase domain 10* / Disintegrin and metalloproteinase domain-containing protein 10 *ENSDARG0000005346823
adam10b / ADAM metallopeptidase domain 10b / ADAM10* / O14672* / ADAM metallopeptidase domain 10*ENSDARG0000001550220
si:ch1073-396h14.1ENSDARG0000005759016


Protein motifs (from Interpro)
Interpro ID Name
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR001762  Disintegrin domain
 IPR002870  Peptidase M12B, propeptide
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR032029  ADAM17, membrane-proximal domain
 IPR034025  ADAM10/ADAM17 catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulated proteolysis of p75NTR
TNF signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr