ENSDARG00000043371


Danio rerio

Features
Gene ID: ENSDARG00000043371
  
Biological name :mdh2
  
Synonyms : malate dehydrogenase 2, NAD (mitochondrial) / mdh2
  
Possible biological names infered from orthology : malate dehydrogenase 2 / Malate dehydrogenase, mitochondrial / P08249 / P40926
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 33382858
Gene end: 33394568
  
Corresponding Affymetrix probe sets: Dr.25868.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000063661
NCBI entrez gene - 406405     See in Manteia.
swissprot - Q7T334
ZFIN ID - ZDB-GENE-040426-2143
Ensembl - ENSDARG00000043371
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MDH2ENSGALG00000001949Gallus gallus
 MDH2ENSG00000146701Homo sapiens
 Mdh2ENSMUSG00000019179Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001236  Lactate/malate dehydrogenase, N-terminal
 IPR001252  Malate dehydrogenase, active site
 IPR001557  L-lactate/malate dehydrogenase
 IPR010097  Malate dehydrogenase, type 1
 IPR015955  Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
 IPR016040  NAD(P)-binding domain
 IPR022383  Lactate/malate dehydrogenase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006099 tricarboxylic acid cycle IEA
 biological_processGO:0006108 malate metabolic process IEA
 biological_processGO:0019752 carboxylic acid metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016615 malate dehydrogenase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0030060 L-malate dehydrogenase activity IEA


Pathways (from Reactome)
Pathway description
Gluconeogenesis
Citric acid cycle (TCA cycle)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000043371 mdh2 / malate dehydrogenase 2, NAD (mitochondrial) / P40926* / malate dehydrogenase 2*  / complex






 

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