ENSGALG00000001949


Gallus gallus

Features
Gene ID: ENSGALG00000001949
  
Biological name :MDH2
  
Synonyms : malate dehydrogenase 2 / MDH2
  
Possible biological names infered from orthology : Malate dehydrogenase, mitochondrial / P08249 / P40926
  
Species: Gallus gallus
  
Chr. number: 19
Strand: -1
Band:
Gene start: 4260413
Gene end: 4268042
  
Corresponding Affymetrix probe sets: Gga.19877.1.S1_at (Chicken Array)   Gga.4839.1.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000003012
Ensembl peptide - ENSGALP00000063163
Ensembl peptide - ENSGALP00000060413
Ensembl peptide - ENSGALP00000058489
NCBI entrez gene - 417517     See in Manteia.
RefSeq - XM_415765
swissprot - E1BVT3
swissprot - A0A1L1RWF4
swissprot - A0A1L1RNR3
swissprot - A0A1D5PZS3
Ensembl - ENSGALG00000001949
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mdh2ENSDARG00000043371Danio rerio
 MDH2ENSG00000146701Homo sapiens
 Mdh2ENSMUSG00000019179Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001236  Lactate/malate dehydrogenase, N-terminal
 IPR001252  Malate dehydrogenase, active site
 IPR001557  L-lactate/malate dehydrogenase
 IPR010097  Malate dehydrogenase, type 1
 IPR015955  Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
 IPR016040  NAD(P)-binding domain
 IPR022383  Lactate/malate dehydrogenase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006099 tricarboxylic acid cycle IEA
 biological_processGO:0006108 malate metabolic process IEA
 biological_processGO:0006475 internal protein amino acid acetylation IEA
 biological_processGO:0009060 aerobic respiration IEA
 biological_processGO:0019752 carboxylic acid metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043209 myelin sheath IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016615 malate dehydrogenase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0030060 L-malate dehydrogenase activity IEA


Pathways (from Reactome)
Pathway description
Gluconeogenesis
Citric acid cycle (TCA cycle)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001949 MDH2 / malate dehydrogenase 2 / P08249* / P40926* / Malate dehydrogenase, mitochondrial *  / complex






 

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contact: otassy@igbmc.fr